Epidemiologic picture of Kawasaki disease in Korea, 2000-2002
Epidemiologic picture of Kawasaki disease in Korea, 2000-2002
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DOI：
10.1111/j.1442-200x.2005.02079.x
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发表时间：
2005-08-01
影响因子：
1.4
通讯作者：
Tockgo, YC
中科院分区：
文献类型：
--
作者：
Park, YW;Han, JW;Tockgo, YC
背景：本研究的目的是调查2000年至2002年3年间韩国川崎病的发病率和流行病学模式。方法：对川崎病的流行病学进行回顾性调查。对所有112家有儿科住院医师项目的医院进行问卷调查，并对获得的数据进行分析。结果：92家医院的9150例川崎病患者（有效率82.1%）中，男性5515例，女性3635例（男女比例1.52:1）。 2000年每10万名<5岁儿童发病率为73.7例，2001年上升至90.8例，2002年上升至95.5例（平均发病率为86.4例）。 5月、6月和7月的月度患者人数略多。他们的平均发病年龄、兄弟姐妹病例比例和复发病例率分别为 30.5 个月、0.17% 和 2.9%。冠状动脉异常发生率为18.6%，其中冠状动脉扩张为17.3%，动脉瘤为3.1%。结论：<5岁儿童的年平均发病率为86.4/10万，居世界第二位。
Background: The aim of this study was to investigate the incidence rate and epidemiologic patterns of Kawasaki disease in Korea for a 3 year period during 2000 to 2002.Methods: An epidemiologic survey on Kawasaki disease was retrospectively performed. The questionnaire was sent to all 112 hospitals having pediatric residency programs, and obtained data were analyzed.Results: The 9150 cases of Kawasaki disease from 92 hospitals which responded (response rate, 82.1%) included 5515 males and 3635 females (male : female ratio, 1.52:1). The incidence rate per 100 000 children < 5 years old was 73.7 in 2000, and increased to 90.8 in 2001, and 95.5 in 2002 (average rate, 86.4). The monthly number of patients was slightly higher in May, June and July. Their mean age of onset, the proportion of sibling cases, and a rate of recurrent cases were 30.5 months, 0.17%, and 2.9%, respectively. Coronary arterial abnormalities occurred in 18.6% of cases including dilatations of 17.3% and aneurysms of 3.1%.Conclusion: The average annual incidence, 86.4/100 000 in children < 5 years old is the second highest rate in the world.