3D printed CT-based abdominal structure mannequin for enabling research
3D printed CT-based abdominal structure mannequin for enabling research
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DOI：
10.1186/s41205-020-0056-9
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发表时间：
2020-02-05
影响因子：
3.7
通讯作者：
Paul, Narinder
中科院分区：
文献类型：
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作者：
Anwari, Vahid;Lai, Ashley;Paul, Narinder
拟人体模是一种放射学上精确的人体组织逼真模型，可用于研究创新成像和介入技术、教育模拟和医学成像设备校准。目前可用的CT体模是用于医学成像设备的校准的适当工具，但对于研究和教育模拟具有主要缺点。它们是昂贵的，当在基于X射线的图像扫描期间可视化时缺乏解剖器官的真实外观和特征。此外，CT体模不是模块化的，因此用户无法出于研究或培训目的从体模内取出特定器官。3D打印技术已经发展，可用于为模块化拟人人体模型打印解剖学上精确的腹部器官，以解决现有模型的局限性。在这项研究中，来自临床患者的CT图像被用于3D打印以下器官外壳：肝脏，肾脏，脾脏以及大肠和小肠。此外，脂肪组织使用蜂蜡建模，肌肉组织使用液体聚氨酯橡胶建模，以匹配CT Hounsfield单位在120 kVp下的真实的组织的放射密度。同样，所有3D打印的器官外壳都填充了琼脂基溶液，以模拟CT Hounsfield单位中120 kVp下真实的组织的放射密度。人体模型在医学成像和教育的各个方面都有应用范围，使我们能够在不需要扫描患者的情况下解决临床重要性的关键领域。
An anthropomorphic phantom is a radiologically accurate, tissue realistic model of the human body that can be used for research into innovative imaging and interventional techniques, education simulation and calibration of medical imaging equipment. Currently available CT phantoms are appropriate tools for calibration of medical imaging equipment but have major disadvantages for research and educational simulation. They are expensive, lacking the realistic appearance and characteristics of anatomical organs when visualized during X-ray based image scanning. In addition, CT phantoms are not modular hence users are not able to remove specific organs from inside the phantom for research or training purposes. 3D printing technology has evolved and can be used to print anatomically accurate abdominal organs for a modular anthropomorphic mannequin to address limitations of existing phantoms. In this study, CT images from a clinical patient were used to 3D print the following organ shells: liver, kidneys, spleen, and large and small intestines. In addition, fatty tissue was made using modelling beeswax and musculature was modeled using liquid urethane rubber to match the radiological density of real tissue in CT Hounsfield Units at 120kVp. Similarly, all 3D printed organ shells were filled with an agar-based solution to mimic the radiological density of real tissue in CT Hounsfield Units at 120kVp. The mannequin has scope for applications in various aspects of medical imaging and education, allowing us to address key areas of clinical importance without the need for scanning patients.