Do different data analytic approaches generate discrepant findings when measuring mother-infant HPA axis attunement?
Do different data analytic approaches generate discrepant findings when measuring mother-infant HPA axis attunement?
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DOI：
10.1002/dev.21474
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发表时间：
2017-03-01
影响因子：
2.2
通讯作者：
Lonstein, Joseph S.
中科院分区：
文献类型：
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作者：
Bernard, Nicola K.;Kashy, Deborah A.;Lonstein, Joseph S.
母亲和婴儿在下丘脑-垂体-肾上腺(HPA)轴对急性应激源的反应之间的协调被认为有利于儿童正在形成的生理和行为自我调节，以及他们的社会情绪发展。然而，文献中没有普遍接受的调谐定义，这似乎导致了确定是否存在调谐的统计分析不一致，并导致了不同的结果。我们使用了一系列数据分析方法，其中一些以前在调谐文献中使用，另一些没有，评估182名妇女和她们一岁的婴儿在HPA轴上对急性应激的调谐反应。在自然的实验室应激源(婴儿手臂束缚)之前和两次之后，从母亲和婴儿的唾液样本中检测皮质醇。数据分析方法的结果好坏参半，一些分析表明存在协调，而另一些则不是。讨论了每种统计方法的优点和缺点，使用交叉滞后模型进行分析似乎是最合适的，该模型同时考虑了时间和母婴之间的互动。在生理调谐的概念化和分析领域中达成更大的共识将是有价值的，以促进我们对这一现象的理解。
Attunement between mothers and infants in their hypothalamic-pituitary-adrenal (HPA) axis responsiveness to acute stressors is thought to benefit the child's emerging physiological and behavioral self-regulation, as well as their socioemotional development. However, there is no universally accepted definition of attunement in the literature, which appears to have resulted in inconsistent statistical analyses for determining its presence or absence, and contributed to discrepant results. We used a series of data analytic approaches, some previously used in the attunement literature and others not, to evaluate the attunement between 182 women and their 1-year-old infants in their HPA axis responsivity to acute stress. Cortisol was measured in saliva samples taken from mothers and infants before and twice after a naturalistic laboratory stressor (infant arm restraint). The results of the data analytic approaches were mixed, with some analyses suggesting attunement while others did not. The strengths and weaknesses of each statistical approach are discussed, and an analysis using a cross-lagged model that considered both time and interactions between mother and infant appeared the most appropriate. Greater consensus in the field about the conceptualization and analysis of physiological attunement would be valuable in order to advance our understanding of this phenomenon.