Maternal pre-pregnant body mass index, maternal weight change and offspring birthweight
Maternal pre-pregnant body mass index, maternal weight change and offspring birthweight
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DOI：
10.1111/j.1600-0412.2011.01321.x
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发表时间：
2012-02-01
影响因子：
4.3
通讯作者：
Nystad, Wenche
中科院分区：
文献类型：
--
作者：
Koepp, Unni Mette Stamnes;Andersen, Lene Frost;Nystad, Wenche
Objective.使用世界卫生组织（WHO）制定并由医学研究所（IOM）于2009年采用的BMI分类，估计孕妇孕前体重指数（BMI）与孕妇妊娠期间体重变化和后代出生体重之间的关联。设计挪威母亲和儿童队列研究（MoBa）是挪威公共卫生研究所进行的基于人群的妊娠队列研究。设置.从挪威所有地理区域招募妇女。人口该研究包括58，383名孕妇。方法. 2000 - 2007年，通过向怀孕17 - 18周的挪威妇女发出邮寄邀请，妇女被纳入研究。线性回归分析是基于怀孕期间两份调查问卷的暴露数据和出生体重数据。主要结果指标。三磅重。结果平均孕前BMI为24 kg/m2（SD 4.3），妊娠前30周的平均母体体重变化为9.3 kg（SD 4.4），平均出生体重为3675 g（SD 487），平均年龄为30.3岁。在这些妇女中，65.2%的人孕前体重正常，2.9%体重不足，22.3%超重，9.5%肥胖（第13类）。校正潜在混杂因素后的线性回归分析显示，后代出生体重随着母亲孕前BMI的增加而增加，并且在所有六种孕前BMI中，随着母亲妊娠期间体重增加而增加。受教育程度最高的妇女其子女出生体重最高。结论在所有六类母体孕前BMI中，后代出生体重随着母体孕前BMI和母体妊娠期间体重增加而增加。
Objective. To estimate the association between maternal pre-pregnant body mass index (BMI) and maternal weight change during pregnancy and offspring birthweight using the BMI classification developed by World Health Organization (WHO) and adopted by the Institute of Medicine (IOM) in 2009. Design. The Norwegian Mother and Child Cohort Study (MoBa) is a population-based pregnancy cohort study conducted by The Norwegian Institute of Public Health. Setting. Women were recruited from all geographic areas of Norway. Population. The study includes 58 383 pregnant women. Methods. Women were enrolled in 20002007 by a postal invitation offered to women in Norway at 1718 weeks of gestation. Linear regression analyses are based on exposure data from two questionnaires during pregnancy and on birthweight data. Main outcome measures. Birthweight. Results. Mean pre-pregnancy BMI was 24kg/m2 (SD 4.3), mean maternal weight change in the first 30 weeks of gestation was 9.3kg (SD 4.4), mean birthweight was 3675g (SD 487) and mean age 30.3 years. Of the women, 65.2% had a normal pre-pregnancy weight, 2.9% were underweight, 22.3% overweight, and 9.5% obese (Classes 13). Linear regression analyses adjusted for potential confounders showed that offspring birthweight increased with increasing maternal pre-pregnant BMI, and with increasing maternal weight gain during pregnancy in all six categories of pre-pregnancy BMI. Women with the highest level of education had the highest offspring birthweight. Conclusion. Offspring birthweight increased with both increasing maternal pre-pregnant BMI and maternal weight gain during pregnancy in all six categories of maternal pre-pregnancy BMI.