Association between maternal exposure to elevated ambient sulfur dioxide during pregnancy and term low birth weight
Association between maternal exposure to elevated ambient sulfur dioxide during pregnancy and term low birth weight
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DOI：
10.1016/j.envres.2004.03.005
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发表时间：
2004-09-01
影响因子：
8.3
通讯作者：
Mao, IF
中科院分区：
文献类型：
--
作者：
Lin, CM;Li, CY;Mao, IF
本回顾性队列研究调查了分娩足月（37-44孕周）低出生体重儿的风险是否与不同孕期空气污染物暴露的差异有关。出生体重低于2500克的足月婴儿（37孕周）被归类为足月低体重婴儿。这项研究的婴儿包括92,288名足月活单胎婴儿，这些婴儿从台湾出生登记处登记，并于1995年至1997年在台湾台北市或高雄市出生。母亲在每个孕期暴露于各种空气污染物（包括CO、SO2、O-3、NO2和PM10）的情况是根据母亲出生时居住地最近的空气质量监测站每日测量的算术平均值估计的。采用校正潜在混杂因素的多变量logistic回归模型来评估特定空气污染物对长期LBW风险的独立影响。这项研究表明，母体环境暴露于SO？浓度超过11.4 ppb的孕妇与低浓度暴露的孕妇相比(最后三个月暴露于12.4 ppb的SO2比低浓度暴露的孕妇早产的风险高20% (OR = 1.20, 95% CI = 1.01-1.41) (
This retrospective cohort study investigated whether the risk of delivering full term (37-44 completed weeks of gestation) low birth weight (LBW) infants is associated with differences in exposure to air pollutants in different trimesters. Full-term infants (37 completed weeks of gestation) with a birth weight below 2500 g were classified as term LBW infants. The study infants comprised 92,288 full-term live singletons identified from the Taiwan birth registry and born in the city of Taipei or Kaoshiung in Taiwan between 1995 and 1997. Maternal exposures to various air pollutants including CO, SO2, O-3, NO2, and PM10 in each trimester of pregnancy was estimated as the arithmetic means of all daily measurements taken by the air quality monitoring station nearest to the district of residence of the mother at birth. The multivariable logistic regression model with adjustment for potential confounders was used to assess the independent effect of specific air pollutants on the risk of term LBW. This study suggested a 26% increase in term LBW risk given maternal ambient exposure to SO? concentration exceeding 11.4 ppb during pregnancy compared to low exposure (12.4 ppb of SO2 in the last trimester showed 20% higher risk (OR = 1.20, 95% CI = 1.01-1.41) of term LBW delivery than mothers with lower exposure (