Research progress in Campylobacter genomic analysis
Research progress in Campylobacter genomic analysis
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DOI：
10.13343/j.cnki.wsxb.20200341
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发表时间：
2021-01-01
期刊：
影响因子：
--
通讯作者：
Huang, Jinlin
中科院分区：
文献类型：
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作者：
Yun, Xi;Jiao, Xin'an;Huang, Jinlin
弯曲杆菌是世界范围内引起肠胃炎的重要人畜共患病原体，对公众健康构成严重威胁。弯曲杆菌的流行、传播和扩散的复杂性与弯曲杆菌的高基因组变异有关。全基因组测序（WGS）是在遗传水平上快速准确地鉴定物种、分析不同个体基因组之间的差异、预测细菌耐药性、毒力基因和群体进化模型的有效工具。本文综述了全基因组测序在弯曲杆菌基因组分析中的应用，以期为弯曲杆菌的流行和防治提供依据。
Campylobacter is an important zoonotic pathogen causing gastroenteritis worldwide, and poses a serious threat to public health. The complexity of prevalence, transmission, and diffusion is associated with high genomic variations of Campylobacter. Whole Genome Sequencing (WGS) is an efficient tool to identify species quickly and accurately, analyze the differences between different individual genomes, predict bacterial resistance, virulence genes and population evolution models on the genetic level. Here we review the application of the whole genome sequencing in Campylobacter genomic analysis to provide a basis for the prevalence and prevention of Campylobacter.