Bright-light exposure during daytime sleeping affects nocturnal melatonin secretion after simulated night work
Bright-light exposure during daytime sleeping affects nocturnal melatonin secretion after simulated night work
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DOI：
10.1080/07420528.2017.1394321
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发表时间：
2018-01-01
影响因子：
2.8
通讯作者：
Wakamura, Tomoko
中科院分区：
文献类型：
--
作者：
Nagashima, Shunsuke;Osawa, Madoka;Wakamura, Tomoko
夜班和轮班工人指南建议，夜间工作后，白天应在黑暗的环境中睡觉。然而，白天呆在黑暗的环境中会减少夜间褪黑激素的分泌并延迟其发作。夜间工作后的日间强光照射对于第二天晚上褪黑激素的合成和维持昼夜节律非常重要。然而，目前尚不清楚夜间工作后的白天睡眠应该在昏暗还是明亮的光线环境中以维持褪黑激素的分泌。因此，本研究的目的是评估白天睡眠期间的强光照射对模拟夜间工作后夜间褪黑激素分泌的影响。 12 名健康男性受试者，年龄 24.8 +/- 4.6（平均值 +/- SD），在两种实验条件（强光或昏暗光）下以随机顺序参加为期 3 天的课程。第一天，受试者于16:00进入实验室，18:00至00:00在弱光条件下每小时采集唾液样本。 00:00至08:00之间，他们参与模拟夜间工作的任务。第二天早上10:00，他们在强光条件下（>3000lx）或弱光条件下（>3000lx）睡了6个小时。
The guidelines for night and shift workers recommend that after night work, they should sleep in a dark environment during the daytime. However, staying in a dark environment during the daytime reduces nocturnal melatonin secretion and delays its onset. Daytime bright-light exposure after night work is important for melatonin synthesis the subsequent night and for maintaining the circadian rhythms. However, it is not clear whether daytime sleeping after night work should be in a dim- or a bright-light environment for maintaining melatonin secretion. The aim of this study, therefore, was to evaluate the effect of bright-light exposure during daytime sleeping on nocturnal melatonin secretion after simulated night work. Twelve healthy male subjects, aged 24.8 +/- 4.6 (mean +/- SD), participated in 3-day sessions under two experimental conditions, bright light or dim light, in a random order. On the first day, the subjects entered the experimental room at 16:00 and saliva samples were collected every hour between 18:00 and 00:00 under dim-light conditions. Between 00:00 and 08:00, they participated in tasks that simulated night work. At 10:00 the next morning, they slept for 6hours under either a bright-light condition (>3000lx) or a dim-light condition (