Antifungal activity of transparent nanocomposite thin films of pullulan and silver against Aspergillus niger
Antifungal activity of transparent nanocomposite thin films of pullulan and silver against Aspergillus niger
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DOI：
10.1016/j.colsurfb.2012.09.045
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发表时间：
2013-03-01
影响因子：
5.8
通讯作者：
Trindade, Tito
中科院分区：
文献类型：
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作者：
Pinto, Ricardo J. B.;Almeida, Adelaide;Trindade, Tito
银主要作为抗菌剂进行研究，较少作为杀真菌剂进行研究，其中涉及抗微生物性质。在这项研究中，普鲁兰多糖和银纳米粒子（NP）的复合膜对尼日尔曲霉的抗真菌活性进行了评估，使用标准协议。这些新材料由含多糖的Ag水溶胶制成透明的流延膜（66-74 μ m厚）。在这种银纳米复合膜的存在下观察到真菌生长抑制。此外，A.首次用扫描电子显微镜（SEM）对尼日尔进行了研究。这种效果发生在纳米复合材料的存在下，由于银NP分散在普鲁兰多糖填料。这种多糖在这里用作生物相容性基质，因此使这些纳米复合材料有利于抗真菌包装材料的开发。(c)2012爱思唯尔有限公司版权所有。
Silver has been mainly investigated as an antibacterial agent and less as a fungicide in which concerns antimicrobial properties. In this research, the antifungal activity of composite films of pullulan and Ag nanoparticles (NP) against Aspergillus niger was evaluated using standard protocols. These new materials were prepared as transparent cast films (66-74 mu m thickness) from Ag hydrosols containing the polysaccharide. Fungal growth inhibition was observed in the presence of such silver nanocomposite films. Moreover, disruption of the spores cells of A. niger was probed for the first time by means of scanning electron microscopy (SEM). This effect occurred in the presence of the nanocomposites due to Ag NP dispersed as fillers in pullulan. This polysaccharide was used here as a biocompatible matrix, hence making these nanocomposites beneficial for the development of antifungal packaging materials. (c) 2012 Elsevier B.V. All rights reserved.