EFFECTS OF ARTIFICIAL MENOPAUSE ON PLASMA AND URINE CALCIUM AND PHOSPHATE
EFFECTS OF ARTIFICIAL MENOPAUSE ON PLASMA AND URINE CALCIUM AND PHOSPHATE
复制标题
人工绝经对血浆和尿液钙和磷酸盐的影响
DOI：
10.1111/j.1365-2265.1972.tb00377.x
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发表时间：
1972
影响因子：
3.2
通讯作者：
B. Nordin
中科院分区：
文献类型：
--
作者：
J. Gallagher;M. M. Young;B. Nordin
测定了9例卵巢切除患者和11例单纯子宫切除患者手术前后血、尿钙、磷的变化。卵巢切除后，平均血浆和空腹尿钙显著升高，24小时平均钙升高37毫克，但并不显著。单独子宫切除术并没有引起血浆或尿钙的显著变化。两组患者的血磷、尿磷变化较小，均未达到显着性水平。6例卵巢切除患者术后尿羟脯氨酸/肌酐比值明显升高，子宫切除术后无明显变化。提示卵巢切除术后血钙和尿钙升高是由于骨吸收增加，而单纯子宫切除术后不会出现这种情况。
Plasma and urine calcium and phosphate were determined in nine patients before and after oophorectomy and in eleven patients before and after simple hysterectomy. Oophorectomy was followed by a significant rise in the mean plasma and fasting urine calcium, and a mean rise of 37 mg in the 24 hr calcium which, however, was not significant. Hysterectomy alone caused no significant change in plasma or urine calcium. In both groups only small changes were observed in plasma and urine phosphate and these did not reach the level of significance. The mean urine hydroxyproline/creatinine ratio rose significantly in six patients after oophorectomy but did not change after hysterectomy. It is suggested the rise in plasma and urine calcium following oophorectomy is due to increased bone resorption which does not occur after simple hysterectomy.