RECENT STUDIES ON THE ZOOPHARMACOGNOSY, PHARMACOLOGY AND NEUROTOXICOLOGY OF SESQUITERPENE LACTONES
RECENT STUDIES ON THE ZOOPHARMACOGNOSY, PHARMACOLOGY AND NEUROTOXICOLOGY OF SESQUITERPENE LACTONES
复制标题
DOI：
10.1055/s-2006-958055
复制
发表时间：
1995-06-01
期刊：
影响因子：
2.7
通讯作者：
RODRIGUEZ, E
中科院分区：
文献类型：
--
作者：
ROBLES, M;AREGULLIN, M;RODRIGUEZ, E
本文介绍了倍半萜内酯（sql）生物活性的最新研究进展，其中一些sql已被确定为动物食用植物的重要成分，具有一定的药用价值，是动物生药学研究的热点。本文讨论了近年来parthenin和upatoriopicrin的体内抗肿瘤研究以及脱氢白血素抗溃疡活性的报道。最近有报道称海伦娜林有强心作用。列宾的神经毒性研究也得到了强调，列宾是一种化合物，据报道会导致马患上类似帕金森病的疾病。
Aspects of recent research on the biological activities of sesquiterpene lactones (SQLs) are presented, Several SQLs have been identified as important constituents of plants consumed by animals for presumed medicinal value and is a focus of research in zoopharmacognosy. Recent in vivo antitumor studies with parthenin and eupatoriopicrin are discussed as well as the reports of the antiulcer activity of dehydroleucodin. Helenalin has recently been reported to have cardiotonic activity. Research on the neurotoxicity of repin, a compound reported to cause a Parkinson's-like disease in horses, is also highlighted.