A community-based study of reporting demographic and clinical information concordance between informants and cognitively impaired participants.
A community-based study of reporting demographic and clinical information concordance between informants and cognitively impaired participants.
复制标题
一项基于社区的研究，报告知情者和认知障碍参与者之间的人口统计和临床信息一致性。
DOI：
10.1007/s40520-023-02435-6
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发表时间：
2023
影响因子：
4
通讯作者：
Morgenstern,LewisB
中科院分区：
文献类型：
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作者：
Khan,Noreen;Briceño,EmilyM;Mehdipanah,Roshanak;Lewandowski-Romps,Lisa;Heeringa,StevenG;Garcia,Nelda;Levine,DeborahA;Langa,KennethM;Morgenstern,LewisB
背景了解知情者和认知受损参与者信息报告之间的一致性对于阿尔茨海默氏症和阿尔茨海默氏症相关痴呆症研究至关重要。方法科珀斯克里斯蒂认知中的脑攻击监测是一项基于社区的队列研究。随机识别美国德克萨斯州纽埃西斯县的家庭。 330 名参与者及其指定的线人回答了问题。生成模型来检查哪些预测因素（包括年龄、性别、种族、认知功能以及与线人的关系）会影响答案的不一致。结果对于人口统计项目，女性参与者和以配偶/伴侣为线人的参与者的不一致程度显着降低，发病率比 (IRR) 分别为 0.65 (CI = 0.44, 0.96) 和 0.41 (CI = 0.23， 0.75），分别。对于健康项目，参与者更好的认知功能与更少的不一致相关，IRR 为 0.85 (CI = 0.76, 0.94)。结论人口统计信息一致性与性别和信息者-参与者关系最相关。认知功能水平与健康信息的一致性最相关。ClinicalTrials.gov 标识符 NCT03403257。
BackgroundUnderstanding concordance between informants’ and cognitively impaired participants’ information reporting is crucial for Alzheimer’s and Alzheimer’s-related dementia studies.MethodsThe Brain Attack Surveillance in Corpus Christi-Cognitive is a community-based cohort study. Households in Nueces County, Texas, USA, were randomly identified. 330 dyads of participants and their named informants answered questions. Models were generated to examine which predictors, including age, gender, ethnicity, cognitive function, and relationship to informant, influenced answer discordance.ResultsFor demographic items, female participants and participants with spouses/partners as informants had significantly less discordance, with incidence rate rations (IRRs) of 0.65 (CI = 0.44, 0.96) and 0.41 (CI = 0.23, 0.75), respectively. For health items, better cognitive function of the participant was associated with less discordance, with an IRR of 0.85 (CI = 0.76, 0.94).ConclusionsDemographic information concordance is most associated with gender and informant–participant relationship. Level of cognitive function is most associated with concordance for health information.ClinicalTrials.gov identifier NCT03403257.