Suboptimal glycemic control, independently of QT interval duration, is associated with increased risk of ventricular arrhythmias in a high-risk population
Suboptimal glycemic control, independently of QT interval duration, is associated with increased risk of ventricular arrhythmias in a high-risk population
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DOI：
10.1111/j.1540-8159.2006.00298.x
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发表时间：
2006-01-01
影响因子：
1.8
通讯作者：
Scarabelli, TM
中科院分区：
文献类型：
--
作者：
Chen-Scarabelli, C;Scarabelli, TM
Background: Although cardiovascular disease is the leading cause of mortality in diabetic patients, little is known about the impact of glycemic control on ventricular tachycardia (VT). Objective: To investigate whether hemoglobin A1c (HbA1c) is associated with increased incidence of VT.Methods: A retrospective study of 336 implantable cardioverter-defibrillator patients (both diabetes mellitus (DM) and non-DM) was conducted.Results: HbA1c levels between 8% and 10% had a significant association with spontaneous VT, but not with QT/QTc.Conclusions: Glycemic index is a significant predictor of spontaneous VT, independently of QT interval. Optimal glycemic control may help reduce occurrence of VT and sudden cardiac death in high-risk DM patients.
