Quantitative Prediction of Critical Amino Acid Positions for Protein Folding
Quantitative Prediction of Critical Amino Acid Positions for Protein Folding
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DOI：
10.2174/092986609789353673
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发表时间：
2009-01-01
影响因子：
1.6
通讯作者：
Eliopoulos, Elias
中科院分区：
文献类型：
--
作者：
Thireou, Trias;Atlamazoglou, Vassilios;Eliopoulos, Elias
MIR算法提供从头开始预测蛋白质的核心残基。一个改进的版本，MIR2，提出并验证了3203蛋白从PDB。结构在闭环中分解，其极限构成观察到的核心残差。它们是由MIR2预测的，准确率接近80%。
The MIR algorithm provides an ab initio prediction of a protein's core residues. An improved version, the MIR2, is presented and validated on 3203 proteins from PDB. Structures are decomposed in Closed Loops, their limits constituting the observed core residues. They are predicted by MIR2 with an accuracy approaching 80%.