Left Ventricular Ejection Fraction (EF) of 55% as Cutoff for Late Transition From Heart Failure (HF) With Preserved EF to HF With Mildly Reduced EF
Left Ventricular Ejection Fraction (EF) of 55% as Cutoff for Late Transition From Heart Failure (HF) With Preserved EF to HF With Mildly Reduced EF
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DOI：
10.1253/circj.cj-15-0425
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发表时间：
2015-10-01
影响因子：
3.3
通讯作者：
Saito, Yoshihiko
中科院分区：
文献类型：
--
作者：
Ueda, Tomoya;Kawakami, Rika;Saito, Yoshihiko
背景：左心室射血分数保留（HFpEF）的心力衰竭（HF）是一种具有复杂病理生理学的综合征。对于 HFpEF 患者随时间推移 LVEF 的变化知之甚少。关于 HFpEF 的一个基本临床问题是 HFpEF 是否是 LVEF 降低的心力衰竭 (HFrEF) 的早期表现。如果是这样，哪些 HFpEF 患者的 LVEF 可能下降至 50% 以下？本研究的目的是检查 HFpEF 患者 LVEF 的纵向变化。方法和结果：在 279 名连续急诊入院的 HFpEF 患者中，我们检查了 100 名出院后至少 1 年接受超声心动图检查的患者。 EF>50%被用作HFpEF的定义。从住院到超声心动图随访的平均持续时间为 31.5 个月，11% 的患者出现 LVEF
Background: Heart failure (HF) with preserved (HFpEF) left ventricular ejection fraction (LVEF) is a syndrome with complex pathophysiology. Little is known about changes in LVEF that occur over time in HFpEF patients. A fundamental clinical question about HFpEF is whether HFpEF is an early manifestation of HF with reduced LVEF (HFrEF). If so, which patients with HFpEF are likely to show a decline in LVEF to less than 50%? The aim of the present study was to examine longitudinal changes in LVEF in patients with HFpEF.Methods and Results: Among 279 consecutive HFpEF patients admitted as emergencies, we examined 100 who underwent echocardiography at least 1 year after discharge. EF >50% was used as the definition of HFpEF. During a mean duration from hospitalization to follow-up echocardiography of 31.5 months, 11% of patients had LVEF