Contrast-enhanced ultrasound for the preoperative assessment of laryngeal carcinoma: a preliminary study

Contrast-enhanced ultrasound for the preoperative assessment of laryngeal carcinoma: a preliminary study
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超声造影对喉癌术前评估的初步研究

DOI:
10.1177/0284185120950108
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发表时间:
2020-08
期刊:
影响因子:
1.3
通讯作者:
Jing Jin Weng
Jing Jin Weng
中科院分区:
医学4区
文献类型:
--
作者:
Qiao Hu;Shang Yong Zhu;Ruo Chuan Liu;Hong Yu Zheng;Hai Mei Lun;Hai Ming Wei;Jing Jin Weng

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背景超声造影(CEUS)被认为是评价肿瘤微循环的一种有吸引力的成像技术。然而,CEUS评估喉癌的有效性尚不清楚。目的比较超声造影(CEUS)、常规超声及增强CT(CECT)在喉癌诊断及术前T分期中的价值。材料与方法41例喉癌患者术前均行常规高频超声、CEUS及CECT检查。记录喉癌的超声造影特征。比较CEUS与常规US的影像学表现、CECT表现及术后病理检查结果。结果CEUS呈高强化38例,等强化3例。造影剂均匀分布20例,不均匀分布21例,其中16例表现为局部灌注缺损。在增强期,37例观察到快速进入,2例观察到同步进入,2例观察到缓慢进入。25例快速出口,16例缓慢出口。常规US、CEUS和CECT之间的治疗前T分期准确性无显著差异(P ≥ 0.500)。超声造影在评价甲状软骨受累方面具有较高的敏感性和特异性。结论与常规超声和CECT相比,CEUS对喉软骨受侵的T分期准确性和诊断价值较高。
Background Contrast-enhanced ultrasound (CEUS) is considered an attractive imaging technique to evaluate tumor microcirculation. However, the validity of CEUS for assessing laryngeal carcinoma is unclear. Purpose To compare the performance of CEUS with conventional US and contrast-enhanced computed tomography (CECT) in the diagnosis and preoperative T-staging of laryngeal carcinoma. Material and Methods Forty-one consecutive patients with laryngeal carcinoma underwent conventional high-frequency US, CEUS, and CECT before surgery. The CEUS characteristics of laryngeal carcinoma were recorded. The imaging findings of CEUS and conventional US were compared with CECT findings and the postoperative pathological examination. Results CEUS showed hyperenhancement in 38 cases and isoenhancement in three cases. Homogeneous distribution of contrast agent was found in 20 cases and heterogeneous distribution in 21 cases, of which 16 cases showed local perfusion defects. In the enhanced phase, rapid entry was observed in 37 cases, synchronous entry was observed in two cases, and slow entry was observed in two cases. Rapid exit was observed in 25 cases and slow exit was observed in 16 cases. The pretherapeutic T-staging accuracy was not significantly different between conventional US, CEUS, and CECT (P ≥ 0.500). A high sensitivity and specificity were achieved by CEUS in the evaluation of involvement of thyroid cartilage. Conclusion Compared with conventional US and CECT, CEUS has a reliable initial T-staging accuracy and diagnostic properties for detecting laryngeal cartilage invasion.
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