Sample restrictions and the elicitation of a constant willingness to pay per quality adjusted life year

Sample restrictions and the elicitation of a constant willingness to pay per quality adjusted life year
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DOI:
10.1002/hec.4236
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发表时间:
2021-02-10
期刊:
影响因子:
2.1
通讯作者:
Kjaer, Trine
Kjaer, Trine
中科院分区:
医学3区
文献类型:
--
作者:
Nielsen, Jytte Seested;Gyrd-Hansen, Dorte;Kjaer, Trine

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众所周知,在质量调整寿命年(QALY)和支付意愿(WTP)之间获得恒定比例权衡所需的基本理论假设是限制性的,并且经常在经验上被违反。在这篇文章中,我们开始调查当数据被限制为只包括通过一定一致性标准的受访者时,是否可以满足相称性条件(在范围不敏感性和严重性独立性方面)。我们假设,我们对数据的限制越多,就越符合WTP和QALY之间恒定比例权衡的要求。我们回顾了一项QALY调查的欧洲值中的丹麦数据,该调查得出了QALY的个人WTP(WTP-Q)。采用“连锁方法”,受访者首先被要求使用标准赌注(SG)或时间权衡(TTO)方法评估特定的健康状况,然后要求他们的WTP获得0.05和0.1的QALY收益(根据受访者的SG/TTO估值定制)。分析不同的排除标准对两个比例条件的影响,我们发现了反对WTP-Q恒定的强有力的证据。将我们的数据限制为只包括通过最严格一致性标准的受访者,不会影响WTP-Q相称性条件的表现。
It is well established that the underlying theoretical assumptions needed to obtain a constant proportional trade-off between a quality adjusted life year (QALY) and willingness to pay (WTP) are restrictive and often empirically violated. In this paper, we set out to investigate whether the proportionality conditions (in terms of scope insensitivity and severity independence) can be satisfied when data is restricted to include only respondents who pass certain consistency criteria. We hypothesize that the more we restrict the data, the better the compliance with the requirement of constant proportional trade-off between WTP and QALY. We revisit the Danish data from the European Value of a QALY survey eliciting individual WTP for a QALY (WTP-Q). Using a "chained approach" respondents were first asked to value a specified health state using the standard gamble (SG) or the time-trade-off (TTO) approach and subsequently asked their WTP for QALY gains of 0.05 and 0.1 (tailored according to the respondent's SG/TTO valuation). Analyzing the impact of the different exclusion criteria on the two proportionality conditions, we find strong evidence against a constant WTP-Q. Restricting our data to include only respondents who pass the most stringent consistency criteria does not impact on the performance of the proportionality conditions for WTP-Q.