Molecular epidemiology of peste des petits ruminants in Niger: An update
Molecular epidemiology of peste des petits ruminants in Niger: An update
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DOI：
10.1111/tbed.13451
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发表时间：
2019-12-27
影响因子：
4.3
通讯作者：
Yaou, Bachir
中科院分区：
文献类型：
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作者：
Souley, Maman Moutari;Ibrahim, Abdoulkarim Issa;Yaou, Bachir
与许多西非国家一样，尼日尔也经常报告小反刍兽疫的爆发，这是山羊和绵羊的一种重要经济疾病。小反刍兽疫病毒（PPRV）是一种致病病毒，可分为四个遗传上不同的谱系。2018年的一份出版物确定了分别于2001年（谱系I和II）和2013年（谱系IV）在该国传播的三种PPRV谱系。在本研究中，在2011年至2017年期间，从尼日尔各地的山羊和绵羊中收集了更新的样本。12个PPRV阳性样品的特征在于核衣壳蛋白（N）基因的一段测序。序列的系统发育分析仅鉴定出来自谱系II和IV的病毒。分析还表明，来自尼日尔的病毒与来自邻国的PPRV有共同的起源，表明存在跨界移动。
Like many West African countries, outbreaks of peste des petits ruminants (PPR), an economically important disease of goats and sheep, are regularly reported in Niger. The causative virus, peste des petits ruminants virus (PPRV), can be differentiated into four genetically distinct lineages. A publication in 2018 identified three PPRV lineages circulating in the country in 2001 (lineages I and II) and 2013 (lineage IV), respectively. In this present study, more recent samples were collected from goats and sheep in locations throughout Niger between 2011 and 2017. Twelve PPRV-positive samples were characterized by sequencing of a segment of the nucleocapsid protein (N) gene. Phylogenetic analysis of the sequences identified viruses from lineages II and IV only. The analysis also indicated a shared origin of the viruses from Niger with PPRVs from neighbouring countries suggesting transboundary movement.