Oxygen-ozone therapy as support and palliative therapy in 50 cancer patients with fatigue - A short report
Oxygen-ozone therapy as support and palliative therapy in 50 cancer patients with fatigue - A short report
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DOI：
10.26355/eurrev_201811_16432
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发表时间：
2018-11-01
影响因子：
3.3
通讯作者：
Berretta, M.
中科院分区：
文献类型：
--
作者：
Tirelli, U.;Cirrito, C.;Berretta, M.
目的：疲劳可能是由所有癌症治疗引起的，可能是由于组织损伤或死亡细胞衍生产物的堆积。材料和方法：2016年2月至2018年5月，在意大利波德诺内市萨西尔的Mede诊所，我们研究了50例癌症和疲劳患者，其中乳腺癌15例，肺癌12例，结肠癌11例，肾癌5例，前列腺癌3例，黑色素瘤2例，肝细胞癌2例。根据SIOOT(科学氧气臭氧治疗学会)方案进行自动输血(GAE)治疗，每周2次，持续1个月，然后每月2次作为维持治疗。结果：19例正在接受肿瘤治疗，10例已经结束癌症治疗，21例处于姑息性治疗。疲劳严重程度量表用于评估患者的疲劳程度，以评估症状的严重程度，评分从1到7。未发现任何副作用，35例(70%)患者的症状显著改善(50%)。结论：我们的初步数据表明，臭氧疗法是治疗癌症患者疲劳的一种有效的支持性疗法，无论是在癌症治疗期间还是在姑息治疗的情况下，都没有明显的副作用。
OBJECTIVE: Fatigue may be cause by all cancer treatments, maybe because the tissue damage or the build-up of dead cells derived products.PATIENTS AND METHODS: At the Mede Clinic in Sacile, Pordenone, Italy, from February 2016 to May 2018 we studied 50 patients with cancer and fatigue (15 with breast cancer, 12 with lung cancer, 11 with colon cancer, 5 with renal cancer, 3 with prostate cancer, 2 with melanoma and 2 hepatocellular carcinoma). Patients were treated with Auto Hemotransfusion (GAE) according to the SIOOT (Scientific Society of Oxygen Ozone Therapy) protocols, two times a week for one month and then twice monthly as maintenance therapy.RESULTS: Nineteen of them were undergoing neoplastic treatment, 10 had already ended the cancer therapy and 21 were in a palliative setting. The Fatigue Severity Scale was used to assess the extent of fatigue in patients, in order to estimate the severity of the symptom with a score from 1 to 7. No side effects were found, and 35 patients (70%) achieved a significant improvement (> 50%) of the symptoms.CONCLUSIONS: Our preliminary data demonstrate that ozone therapy is a valid supportive therapy for fatigue in cancer patients, both during cancer therapy and in a palliative setting with no significant side effects.