4D affine registration models for respiratory-gated PET
4D affine registration models for respiratory-gated PET
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呼吸门控 PET 的 4D 仿射配准模型
DOI：
10.1109/nssmic.2000.950045
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
R. Huesman
中科院分区：
文献类型：
--
作者：
G. Klein;B. Reutter;R. Huesman
由于与呼吸周期相关的运动，心脏位置会发生相当大的偏移，这种运动会降低心脏门控PET研究的图像质量。对抗这种运动引起的模糊的一种方法是一种自动门控采集，然后使用刚体运动假设重新组合配准的图像体积;然而，呼吸运动引起的心脏变形可能会降低该过程的有效性。我们研究了一个12参数的全球仿射运动模型，用于在舒张末期心脏PET序列中注册不同的呼吸门。为了获得运动的鲁棒估计，设计了4D配准模型，其鼓励相邻呼吸时间帧之间的平滑变化的运动。使用成本函数迭代计算配准参数，该成本函数将最小二乘体素差异测量与从预测先验获得的惩罚相结合。假设恒定速度和仿射模型，从相邻的时间帧计算先验。配准后，计算主伸展比以测量非刚性运动的程度。在来自10名受试者的数据中，超过5%的延伸率是常见的，这表明仿射模型可以提供更好的配准，进而提供比限制于6参数刚体假设的技术更好的运动校正复合体积。
The heart position shifts considerably due to motion associated with the respiratory cycle, and this motion can degrade the image quality of cardiac-gated PET studies. One method to combat this motion-induced blur is a respiratory-gated acquisition followed by recombination of registered image volumes using a rigid-body motion assumption; however, deformation of the heart from respiratory motion may reduce the effectiveness of this procedure. We have investigated a 12-parameter global affine motion model for registration of different respiratory gates in an end-diastolic cardiac PET sequence. To obtain robust estimates of motion, a 4D registration model was devised that encouraged smoothly varying motion between adjacent respiratory time frames. Registration parameters were iteratively calculated using a cost function that combined a least squares voxel difference measure with a penalty obtained from a prediction prior. The prior was calculated from adjacent time frames assuming constant velocity and an affine model. After registration, the principal extension ratios were calculated to measure the degree of non-rigid motion. In data from 10 subjects, extension ratios of over 5% were common, indicating that an affine model may provide better registrations and in turn, better motion-corrected composite volumes than could a technique restricted to the 6-parameter rigid body assumption.
使用数学心脏躯干模型评估左右心室容量和射血分数。
DOI：
--
发表时间：
1997
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
影响因子：
--
作者：
Pretorius,PH;Xia,W;King,MA;Tsui,BM;Pan,TS;Villegas,BJ
通讯作者：
Villegas,BJ
影响因子：
1.3
作者：
Woods, RP;Grafton, ST;Mazziotta, JC
通讯作者：
Mazziotta, JC