Supranuclear disturbances of ocular motility in Lytico‐Bodig
Supranuclear disturbances of ocular motility in Lytico‐Bodig
复制标题
Lytico-Bodig 眼运动的核上障碍
作者：
Frederick E. Lepore;John C. Steele;Terry A. Cox;G. Tillson;D. B. Calne;R. Duvoisin;L. Lavine;J. V. McDarby
我们在37例肌萎缩侧索硬化症/帕金森-痴呆复合体(Lytico-BoDigi，肌萎缩侧索硬化症/帕金森-痴呆复合体)患者中发现了异常的核上眼球或眼睑运动。追踪性瘫痪21例，前庭-眼反射(VOR)消除异常18例，会聚异常15例，视动性眼球震颤(OKN)异常13例，共轭注视受限12例，眼球震颤9例，眼球跳动障碍9例，注视异常6例。眼睑异常包括21例眉间反射亢进，3例非自主性提肌抑制，2例眼睑痉挛。早期的报道显示眼球突出症并不常见，但是现在我们发现核上性眼球和眼睑的缺陷是普遍的，有时非常突出。
We found abnormal supranuclear ocular or lid motility in all of 37 patients with Lytico-Bodig (amyotrophic lateral sclerosis/parkinsonism-dementia complex). Twenty-one patients had pursuit paresis, 18 abnormal vestibulo-ocular reflex (VOR) cancellation, 15 abnormal convergence, 13 abnormal optokinetic nystagmus (OKN), 12 conjugate gaze limitation, nine nystagmus, nine saccadic paresis, and six abnormal fixation. Lid abnormalities included glabellar hyperreflexia in 21, involuntary levator inhibition in three, and blepharospasm in two. Earlier reports have indicated infrequent ocular disturbances in Lytico-Bodig, but we now find supranuclear eye and lid deficits are universal and sometimes very prominent.
影响因子：
56.9
作者：
SPENCER, PS;NUNN, PB;ROBERTSON, RC
通讯作者：
ROBERTSON, RC