Toxins produced in cyanobacterial water blooms - toxicity and risks.
Toxins produced in cyanobacterial water blooms - toxicity and risks.
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DOI：
10.2478/v10102-009-0006-2
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发表时间：
2009-06
影响因子：
--
通讯作者：
Maršálek B
中科院分区：
文献类型：
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作者：
Bláha L;Babica P;Maršálek B
蓝藻在淡水中的大量繁殖是全球范围内主要的生态和人类健康问题。本文综述了主要的蓝藻毒素（肝毒素、神经毒素等）的研究进展，重点介绍了具有高急性和慢性毒性的环七肽微囊藻毒素。除了讨论人类健康风险外，还强调了微囊藻毒素的生态毒理学和随之而来的生态风险。尽管对微囊藻毒素的研究已经得到了很大的关注，但蓝藻细菌会产生一系列目前未知的毒素，这需要研究的关注。进一步的研究还应该解决不同类别的蓝藻代谢物之间可能的加性、增效或拮抗作用，以及与其他有毒应激源（如金属或持久性有机污染物）的相互作用。
Cyanobacterial blooms in freshwaters represent a major ecological and human health problem worldwide. This paper briefly summarizes information on major cyanobacterial toxins (hepatotoxins, neurotoxins etc.) with special attention to microcystins-cyclic heptapeptides with high acute and chronic toxicities. Besides discussion of human health risks, microcystin ecotoxicology and consequent ecological risks are also highlighted. Although significant research attention has been paid to microcystins, cyanobacteria produce a wide range of currently unknown toxins, which will require research attention. Further research should also address possible additive, synergistic or antagonistic effects among different classes of cyanobacterial metabolites, as well as interactions with other toxic stressors such as metals or persistent organic pollutants.