Development of the Taste Bud

Development of the Taste Bud
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味蕾的发育

DOI:
10.1007/978-3-642-65245-5_3
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发表时间:
1971
期刊:
影响因子:
--
通讯作者:
A. Farbman
A. Farbman
中科院分区:
--
文献类型:
--
作者:
A. Farbman

文献摘要

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发育生物学家面临的主要问题之一是控制细胞分化的确切性质。在后生动物中,这些控制的研究是困难的,因为众多的细胞类型和复杂性。生物学家已经能够观察发育过程中的事件,并对发生的复杂变化模式进行详细描述。从他们的描述性叙述和实验操作中可以看出,发展取决于一组极其复杂的机制,这些机制在适当的时间和适当的顺序中受到微妙的控制。从生物学家的观点来看,研究这些机制的最好方法是将它们分解为最简单的元素,并将注意力集中在其中之一上。味蕾可以被认为是这些“简单的元素”之一。由于其体积小,形态独特,易于获得,它为细胞分化的研究提供了一些明显的优势。本章将对味蕾发育的研究现状进行总结和评价。
One of the major problems confronting developmental biologists is the precise nature of the controls governing cell differentiation. In Metazoa, the study of these controls is made difficult because of the numerous cell types and then-complexity. Biologists have been able to observe developmental events as they progress and to make detailed descriptions of the complex patterns of change that occur. It is implicit from their descriptive accounts and experimental manipulations that development depends on an extraordinarily complex group of delicately controlled mechanisms operating at the proper time and in proper sequence. From the standpoint of the biologist, the best way to approach the study of these mechanisms is to resolve them into their simplest elements and to focus attention on one of these. The taste bud may be considered one of these “simpler elements.” Because of its small size, distinct morphology, and easy accessibility, it offers some distinct advantages for the study of cell differentiation. In this chapter the current status of knowledge of taste bud development will be summarized and evaluated.