Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer's Disease, and Vascular Dementia in Older Adults.
Physical Activity: A Viable Way to Reduce the Risks of Mild Cognitive Impairment, Alzheimer's Disease, and Vascular Dementia in Older Adults.
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DOI：
10.3390/brainsci7020022
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发表时间：
2017-02-20
期刊：
影响因子：
3.3
通讯作者：
Hongu N
中科院分区：
文献类型：
--
作者：
Gallaway PJ;Miyake H;Buchowski MS;Shimada M;Yoshitake Y;Kim AS;Hongu N
最近发达国家神经退行性疾病的惊人增长是影响老年人的主要医学问题之一。在这篇综述中，我们提供了体力活动（PA）与主要与年龄相关的神经退行性疾病和综合征的相关信息，包括阿尔茨海默病、血管性痴呆和轻度认知障碍。我们还提供了PA在降低这些疾病风险和帮助改善老年人认知结果方面的作用的证据。最后，我们描述了这种保护作用发生的一些潜在机制，为未来的研究提供指导。
A recent alarming rise of neurodegenerative diseases in the developed world is one of the major medical issues affecting older adults. In this review, we provide information about the associations of physical activity (PA) with major age-related neurodegenerative diseases and syndromes, including Alzheimer’s disease, vascular dementia, and mild cognitive impairment. We also provide evidence of PA’s role in reducing the risks of these diseases and helping to improve cognitive outcomes in older adults. Finally, we describe some potential mechanisms by which this protective effect occurs, providing guidelines for future research.