Performance of the Visual Field Index in Glaucoma Patients With Moderately Advanced Visual Field Loss
Performance of the Visual Field Index in Glaucoma Patients With Moderately Advanced Visual Field Loss
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DOI：
10.1016/j.ajo.2013.09.003
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发表时间：
2014-01-01
影响因子：
4.2
通讯作者：
Caprioli, Joseph
中科院分区：
文献类型：
--
作者：
Lee, Jun Mo;Cirineo, Nila;Caprioli, Joseph
目得：目的探讨中晚期视野损害青光眼患者视野指数（VFI）与视野平均偏差（MD）的关系，并确定纵向视野（VF）序列中MD超过-20 dB时，VFI估计策略由模式偏差概率值变为总偏差概率值时VFI边界效应的大小。“设计：纵向数据分析的回顾性队列研究方法：MD和VFI值进行VF测试148眼的148青光眼患者MD约-20 dB进行了研究。共纳入1286个VF，MD值在-16 dB至-24 dB范围内。将眼睛分为2组，第一组的连续MD均优于或均低于-20 dB，第二组的连续MD超过-20 dB值。MD的变化（MD）定义为2个连续VF的MD值之间的绝对差值。根据相同VF的2个VFI值，VFI变化的绝对值计算（Delta VFI）。的装置Delta VFI的（+/-标准差）为4.17%两侧MD均在-20 dB组中的平均视力为15.8%（+/- 3.3%），MD超过-20 dB组中的平均视力为15.8%（+/- 8.4%）（P < .0001）。对于Delta VFI/Delta MD，这些值为6.8%/dB（+/- 10.5%），当MD福尔斯的范围落在-20 dB的两侧时，以及7.9%/dB（+/- 6.2%）当MD范围超过-20 dB值时（P = .042）。结论：VFI的值在具有跨越-20 dB的MD的眼睛的系列VP中变得高度可变，与在-20 dB的任一侧上与MD相关联的那些VFI相比。该效应的可能性是在MD的-20 dB处计算VFI所包括的点中从使用模式偏差概率值到总偏差概率值的变化。发展指标来衡量VF率是从这个边界效应中的中度进展性青光眼是可取的。(C)2014由Elsevier Ltd.出版
PURPOSE: To explore the relationship between the visual field index (VFI) and the visual field mean deviation (MD) in glaucoma patients with moderately advanced perimetric damage and to identify the magnitude of the boundary effect of VFI that occurred when the VFI estimation strategy changed from pattern deviation probability value to total deviation probability value as the MD crossed -20 dB in longitudinal visual field (VF) series. " DESIGN: A retrospective cohort study of longitudinal data analysis.METHODS: The MD and VFI values obtained from VF tests conducted on 148 eyes of 148 glaucoma patients having an MD around -20 dB were studied. A total of 1286 VFs with MD values within the range of -16 dB to -24 dB were included. The eyes were divided into 2 groups, with the first having serial MDs all better than or all worse than -20 dB and the second with serial MDs crossing the -20 dB value. Change in MD (MD) was defined as the absolute difference between the MD values of 2 consecutive VFs. Based on the 2 VFI values of the same VFs, the absolute value of change in VFI (Delta VFI) was calculated.RESULTS: The means (+/- standard deviation) for the Delta VFI were 4.17% (+/- 3.3%) in the group of eyes with MDs on either side of -20 dB, and were 15.8% (+/- 8.4%) in the group with MDs crossing -20 dB (P < .0001). For Delta VFI/Delta MD, these values were 6.8%/dB (+/- 10.5%) when the range of MD falls on either side of -20 dB, and 7.9%/dB (+/- 6.2%) when the range of MD crosses the -20 dB values (P = .042).CONCLUSIONS: The values of the VFI become highly variable in serial VPs of eyes with MDs crossing -20 dB, in comparison to those VFIs associated with MDs on either side of -20 dB. The likelihood for this effect is the change from use of pattern deviation probability value to total deviation probability value in the points included in the calculation of VFI at -20 dB of MD. The development of indices to measure VF rates that are free from this boundary effect in moderately advanced glaucoma is desirable. (C) 2014 Published by Elsevier Ltd.