Modified Implant Surface with Slower and Less Initial Biofilm Formation
Modified Implant Surface with Slower and Less Initial Biofilm Formation
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DOI：
10.1111/cid.12140
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发表时间：
2015-06-01
影响因子：
3.6
通讯作者：
Schwarz, Frank
中科院分区：
文献类型：
--
作者：
John, Gordon;Becker, Juergen;Schwarz, Frank
种植体周围黏膜炎和种植体周围炎是牙种植学中的一个重要问题。种植体周围感染主要由生物膜的形成引起。不同的表面纹理表现出不同的条件，导致在几个速度的成熟和development.Materials和MethodsOn三个不同的钛种植体表面，加工表面（M），喷砂大砂砾，酸蚀表面（SLA）和加工改性酸蚀表面（mod MA）的初始生物膜的形成。通过赤藓红染色和能量色散X射线光谱（EDX）研究斑块形成。为了测试这些菌斑沉降表面的生物相容性，高压灭菌标本与人牙龈成纤维细胞，细胞活力进行了test.ResultsThe平均初始菌斑表面检测在以下降序：M>SLA>mod MA。这些组之间的差异是显著的。在M组中检测到最高的细胞活力，而mod MA和SLA显示出相当的结果。结论在本研究的范围内，Mod MA表面初始生物膜形成速度明显减慢，这可能是一个优势，也有利于患者的口腔卫生，因为菌斑成熟延迟，不成熟的生物膜更容易去除。
BackgroundPeri-implant mucositis and peri-implantitis are a raising issue in dental implantology. Peri-implant infections are mainly caused by the formation of biofilm. Different surface textures exhibit various conditions for biofilm formation resulting in several speed of maturation and development.Materials and MethodsOn three different titanium implant surfaces, machined-surface (M), sandblasted large grit, and acid-etched surface (SLA) and machined-modified acid-etched surface (mod MA) initial biofilms were collected. Plaque formation was investigated by erythrosine staining and energy-dispersive X-ray spectroscopy (EDX). For testing the biocompatibility of these plaque-settled surfaces, autoclaved specimens were settled with human gingival fibroblasts, and cell viability was tested.ResultsThe mean initial plaque surface was detected in the following descending order: M>SLA>mod MA. The differences between these groups were significant. The highest cell viability was detected in the M groups, whereas mod MA and SLA showed comparable results. The results of initial biofilm formation were proved by EDX.ConclusionsWithin the limitations of this study, conclusion can be made that mod MA surface shows significant slower initial biofilm formation which could be an advantage in initial transgingival healing process and also an easement for oral hygiene of patients because maturation of plaque is retarded, and immature biofilms are easier to remove.