Statistical mechanics of supercoils and the torsional stiffness of the DNA double helix
Statistical mechanics of supercoils and the torsional stiffness of the DNA double helix
复制标题
超螺旋的统计力学和 DNA 双螺旋的扭转刚度
作者：
A. Vologodskii;V. Anshelevich;A. Lukashin;M. Frank
用蒙特-卡罗方法计算了封闭无结高分子链在扭体数上的分布。对于环状双链DNA，分布的方差约等于在连接数上观察到的平衡分布方差的一半。由DNA扭曲的波动引起的平衡使得有可能估计双螺旋的扭转刚度。
The distribution of closed unknotted polymer chains over the writhing number is calculated by the Monte-Carlo method. For circular duplex DNA the variance of the distribution equals approximately half the observed variance of equilibrium distribution over the linking number. The balance which arises from fluctuations in DNA twisting makes it possible to estimate the torsional stiffness of the double helix.