Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients
Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patients
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DOI：
10.1097/hjr.0b013e32801da137
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发表时间：
2007-06-01
影响因子：
--
通讯作者：
Lai, Ming-May
中科院分区：
文献类型：
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作者：
Huang, Chien-Fang;Li, Tsai-Chung;Lai, Ming-May
背景：几种血脂比值可能是冠心病风险的预测因子。我们评估的疗效Monopolyspurpureus Went大米（红曲米）降低lipidratis.Method和结果我们评估了79高胆固醇血症患者（年龄23-65岁）谁收到了每日两次剂量的红曲米或安慰剂在600毫克8周。治疗8周后，治疗组患者的低密度脂蛋白胆固醇、总胆固醇/高密度脂蛋白胆固醇、低密度脂蛋白胆固醇/高密度脂蛋白胆固醇、载脂蛋白13/载脂蛋白A-1比值均显著低于对照组。
Background Several lipid ratios may be predictors of coronary artery disease risk. We assessed the efficacy of Monascus purpureus Went rice (red yeast rice) on lowering lipid ratios.Method and results We evaluated 79 hypercholesterolemic patients (aged 23-65 years) who received a twice-daily dose of either red yeast rice or a placebo at 600 mg for 8 weeks. The 8-week treatment with red yeast rice showed significantly greater reduction than the placebo treatment in low-density lipoprotein cholesterol levels, total cholesterol/high-clensity lipoprotein cholesterol, low-density lipoprotein cholesterol/high-density lipoprotein cholesterol and apolipoprotein 13/apolipoprotein A-1 ratios.Conclusions Red yeast rice can reduce lipid ratios in hypercholesterolemic patients.