Steroidal saponins from the roots of Smilax aspera subsp. mauritanica.
Steroidal saponins from the roots of Smilax aspera subsp. mauritanica.
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DOI：
10.1055/s-0028-1084369
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发表时间：
2008-07
影响因子：
1.7
通讯作者：
Zineddine Belhouchet;M. Sautour;T. Miyamoto;M. Lacaille‐Dubois
中科院分区：
文献类型：
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作者：
Zineddine Belhouchet;M. Sautour;T. Miyamoto;M. Lacaille‐Dubois
从 Smilax aspera subsp. 的根中分离出两种新的甾体皂苷 (1, 2)。毛里塔尼卡 (POIR.) ARCANG。 （百合科），以及已知的 curillin G (3)、天门冬苷 E (4)、门冬苷 A (5)、门冬苷 B (6) 和酚类化合物白藜芦醇 (7)。它们的结构主要是根据 600 MHz 2D-NMR 光谱数据确定的。 3 对人类致病性酵母白色念珠菌、光滑念珠菌和热带念珠菌表现出抗真菌活性（最低抑制浓度分别为 25、25 和 50 微克/毫升），而其他化合物则无活性。
Two new steroidal saponins (1, 2) were isolated from the roots of Smilax aspera subsp. mauritanica (POIR.) ARCANG. (Liliaceae), together with the known curillin G (3), asparagoside E (4), asparoside A (5), asparoside B (6) and the phenolic compound resveratrol (7). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 3 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (minimum inhibitory concentrations of 25, 25 and 50 microg/ml, respectively) whereas the other compounds were inactive.