DIAGNOSIS OF ESOPHAGEAL SPASM BY ERGOMETRINE PROVOCATION

DIAGNOSIS OF ESOPHAGEAL SPASM BY ERGOMETRINE PROVOCATION
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DOI:
10.1136/gut.23.2.89
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发表时间:
1982-01-01
期刊:
GUT
影响因子:
24.5
通讯作者:
HENDERSON, AH
HENDERSON, AH
中科院分区:
医学1区
文献类型:
--
作者:
DAVIES, HA;KAYE, MD;HENDERSON, AH

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食管痉挛可能与心肌缺血的疼痛相似。对42例心绞痛患者进行了心血管疾病检查,直到检查未能显示任何心血管异常。在24例患者中,在食管测压期间麦角新碱激发导致食管动力显著恶化,与熟悉性疼痛相关。以类似的方式检查了10个年龄匹配的对照组,麦角新碱在4例中产生了运动性变化,在2例中产生了疼痛。6名患有冠状动脉狭窄和运动性心绞痛的志愿者在疼痛期间没有发生食管动力学变化。麦角新碱激发可用于诊断复发性心绞痛样疼痛但无贲门异常的患者的痉挛。
Esophageal spasm may mimic the pain of myocardial ischemia. Patients (42) who were through to have angina, until investigations failed to show any cardiovascular abnormality, were examined for esophgeal disease. Ergometrine provocation during esophgeal manometry caused significant deterioration in esophageal motility, associated with familiar pain, in 24 patients. Ten age-matched controls were examined in a similar way, and ergometrine produced motility changes in 4 and pain in 2. Six volunteers with coronary artery stenosis and exercise-induced angina did not develop esophageal motility changes during the pain. Ergometrine provocation is useful in establishing the diagnosis of esophgeal spasm in patients with recurrent angina-like pain, but no cardia abnormality.