Evaluation of Immunoglobulin G Absorption from Goat Colostrum by Newborn Piglets
Evaluation of Immunoglobulin G Absorption from Goat Colostrum by Newborn Piglets
复制标题
新生仔猪从山羊初乳中吸收免疫球蛋白 G 的评价
DOI：
10.3390/ani10040637
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
F. Hernández
中科院分区：
文献类型：
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作者：
Silvia Martínez Miró;Susana Naranjo;J. Madrid;M. J. López;C. J. Sánchez;M. Segura;F. Hernández
为了确保高产母猪所生仔猪摄入足够的初乳，有必要使用母猪初乳替代品。本试验旨在评价仔猪对山羊免疫球蛋白G （IgG）的吸收能力，并研究其对仔猪的影响。结果表明，仔猪对山羊IgG的表观吸收系数为20.9%。此外，仔猪对山羊初乳的耐受性良好，为开发以山羊初乳为基础的新生仔猪饲粮提供了可能。摘要本试验旨在探讨仔猪对山羊初乳免疫球蛋白G （IgG）的吸收情况及其对哺乳仔猪的潜在影响。将38头体重在1000 ~ 1700 g之间的仔猪分为三组：正常哺乳的对照组（C组）、猪组和山羊组。后两组仔猪在出生后与母猪分离，在出生后12小时内分别口服20 mL的猪初乳（PC）或山羊初乳（GC）。12 h时IgG的表观吸收效率（AEA）计算为血清总IgG除以摄入的IgG。任何时候均未观察到腹泻或不耐受症状。第20天，3个处理的仔猪体重和死仔猪数基本相同（p < 0.05）。饲喂GC的仔猪12 h血清中山羊IgG的浓度为8.11 mg/mL。山羊IgG和猪IgG的AEA分别为20.9%和26.3% （p < 0.05）。因此，山羊初乳似乎是研究新饲料添加物或人工饲养新生仔猪的一个有前途的选择。
Simple Summary Alternatives to sow colostrum are necessary to ensure adequate colostrum intake by piglets born from hyperprolific sows. This study was conducted to evaluate whether piglets can absorb goat immunoglobin G (IgG) and study its effects on piglets. The results showed that piglets absorbed goat IgG with an apparent coefficient of absorption of 20.9%. In addition, the piglets tolerated goat colostrum well, opening up the possibility of developing supplements based on goat colostrum for newborn piglets. Abstract The aim of this study was to evaluate whether piglets absorb immunoglobin G (IgG) from goat colostrum and the potential effects of its ingestion on suckling piglets. Thirty-eight piglets with body weights ranging from 1000 to 1700 g were assigned to one of the three experimental treatments: Control group (C), where piglets were allowed to suckle normally, and porcine and goat groups. The piglets from the last two groups were removed from the sows after birth and received an oral 20 mL dose every 3 h of porcine (PC) or goat colostrum (GC), respectively, during first 12 h of life. Then, they were returned to newly farrowing sows to continue suckling until 20 d. The apparent efficiency of absorption (AEA) of IgG at 12 h was calculated as total serum IgG divided by ingested IgG. No diarrhea or symptoms of intolerance were observed at any time. On day 20, body weight and the number of dead piglets were similar in all three treatments (p > 0.05). At 12 h, the concentration of goat IgG in the serum of piglets fed GC was 8.11 mg/mL. AEA was 20.9% for goat IgG and 26.3% for porcine IgG (p > 0.05). Therefore, goat colostrum seems a promising alternative to study new feed supplements or artificial rearing of newborn piglets.