Nonalcoholic fatty liver disease as a component of the metabolic syndrome.
Nonalcoholic fatty liver disease as a component of the metabolic syndrome.
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DOI：
10.1007/s11894-008-0012-0
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发表时间：
2008-02-01
影响因子：
--
通讯作者：
Chalasani, Naga
中科院分区：
文献类型：
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作者：
Khashab, Mouen A;Liangpunsakul, Suthat;Chalasani, Naga
非酒精性脂肪性肝病（NAFLD）是肝脏相关疾病发病率和死亡率的重要原因。非酒精性脂肪肝与代谢综合征之间的联系已得到证实：代谢综合征的存在意味着非酒精性脂肪肝患者的组织学进展。新出现的数据表明，NAFLD患者的心血管疾病患病率显著较高。本文综述了这两种综合征的定义，它们之间的联系，以及当它们单独或同时发生时所带来的心血管风险。这篇综述还讨论了综合征的管理选择，包括治疗NAFLD患者代谢综合征的各个组成部分。
Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver-related morbidity and mortality. The association between NAFLD and the metabolic syndrome is well established: the presence of the metabolic syndrome signifies advanced histology in NAFLD patients. Emerging data indicate that patients with NAFLD have a significantly higher prevalence of cardiovascular disease. This article reviews the definitions of the two syndromes, their association, and the cardiovascular risk conferred by both when they occur separately and together. This review also discusses management options for the syndromes, including treating the individual components of the metabolic syndrome in NAFLD patients.