PRIMARY HYPOPHOSPHATEMIC RICKETS - EFFECT OF ORAL PHOSPHATE AND VITAMIN-D ON GROWTH AND SURGICAL-TREATMENT
PRIMARY HYPOPHOSPHATEMIC RICKETS - EFFECT OF ORAL PHOSPHATE AND VITAMIN-D ON GROWTH AND SURGICAL-TREATMENT
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DOI：
10.2106/00004623-198062070-00010
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发表时间：
1980-01-01
影响因子：
5.3
通讯作者：
GAGE, JR
中科院分区：
文献类型：
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作者：
EVANS, GA;ARULANANTHAM, K;GAGE, JR
儿童时期未能诊断和治疗低磷血症性软骨病，导致生长发育迟缓和肢体进行性畸形。当手术治疗畸形时，复发的畸形和截骨术的骨不连，需要进一步的主要手术程序来纠正这些并发症。从儿童早期开始服用口服磷酸盐和维生素D可提高生长速度并控制弓腿畸形的进展。当结果可预测时，残存的内翻畸形可通过胫骨近端干骺端截骨矫正。膝外翻畸形在骨骼成熟之前通过股骨远端骨骺内侧部分的吻合术得到矫正。通过术后早期活动和适当的药物治疗，避免了胫骨延迟愈合和股骨外翻畸形矫正失败的并发症。
Failure to diagnose and treat hypophosphatemic rickets during childhood resulted in stunted growth and progressive deformities of the lower limb. When the deformities were treated surgically, recurrent deformity and non-union of osteotomies developed and further major operative procedures were required to remedy these complications. Treatment from early childhood with oral phosphate and vitamin D improved the rate of growth and controlled the progression of bowleg deformity. Residual varus deformity was corrected by osteotomy through the proximal tibial metaphysis at skeletal maturity when the results were predictable. Genu valgum deformity was corrected by stapling the medial part of the distal femoral epiphysis prior to skeletal maturity. With early postoperative mobilization and adequate medication, the complications of delayed tibial union and failure to correct the femoral valgus deformity were avoided.