Efficiency of Posterior Tibial Nerve Stimulation in Category IIIB Chronic Prostatitis/Chronic Pelvic Pain: A Sham-Controlled Comparative Study

Efficiency of Posterior Tibial Nerve Stimulation in Category IIIB Chronic Prostatitis/Chronic Pelvic Pain: A Sham-Controlled Comparative Study
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DOI:
10.1159/000224865
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发表时间:
2009-01-01
影响因子:
1.6
通讯作者:
Ozden, Hilmi
Ozden, Hilmi
中科院分区:
医学4区
文献类型:
--
作者:
Kabay, Sahin;Kabay, Sibel Canbaz;Ozden, Hilmi

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目的:评价经皮胫后神经电刺激(PTNS)治疗ⅢB类慢性非细菌性前列腺炎/慢性盆腔疼痛综合征的疗效。方法:共有 89 名难治性盆腔疼痛患者被随机分配接受神经刺激 (n = 45) 或假治疗 (n = 44)。美国国立卫生研究院慢性前列腺炎症状指数和视觉模拟量表用于评估干预 12 周后的治疗成功率。客观成功被定义为平均分数至少下降 50%。下降超过 25% 至低于 50% 被认为是部分缓解。结果:12 周 PTNS 后,18 名 (40%) 和 30 名 (66.6%) 患者的疼痛和症状评分出现客观缓解,而 27 名 (60%) 和 15 名 (33.3%) 患者分别出现部分缓解。疼痛和尿急的平均症状评分和视觉模拟评分显着变化,分别从基线时的23.6+/-6.3到基线时的10.2+/-3.6、7.6+/-0.8到基线时的4.3+/-0.6、5.7+/-0.8到3.4+/-0.7。假治疗后,症状、紧迫感和疼痛的评分没有变化。结论:这些结果表明,经皮 PTNS 可以缓解 IIIB 类慢性非细菌性前列腺炎/慢性盆腔疼痛综合征患者的疼痛。版权所有 (C) 2009 S. Karger AG,巴塞尔
Objectives: To evaluate the efficacy of percutaneous posterior tibial nerve stimulation (PTNS) for treatment of the patients with category IIIB chronic non-bacterial prostatitis/chronic pelvic pain syndrome. Methods: A total of 89 patients with therapy-resistant pelvic pain were randomized to receive either nerve stimulation (n = 45) or sham treatment (n = 44). The National Institutes of Health Chronic Prostatitis Symptom Index and visual analogue scale were used to assess treatment success after 12 weeks of intervention. Objective success was defined as a minimum 50% decrease in the mean scores. A decrease of over 25% to below 50% was considered to be a partial response. Results: An objective response was observed with the pain and symptom scores after 12 weeks of PTNS in 18 (40%) and 30 (66.6%) of the patients, whereas a partial response was observed in 27 (60%) and 15 (33.3%) of the patients, respectively. Mean symptom scores and visual analogue scale scores for pain and urgency were significantly changed from 23.6 +/- 6.3 at baseline to 10.2 +/- 3.6, 7.6 +/- 0.8 at baseline to 4.3 +/- 0.6, 5.7 +/- 0.8 at baseline to 3.4 +/- 0.7, respectively. Scores for the symptoms, urgency and pain were not changed with sham treatment. Conclusions: These results have demonstrated that percutaneous PTNS may relieve pain in the patients with category IIIB chronic non-bacterial prostatitis/chronic pelvic pain syndrome. Copyright (C) 2009 S. Karger AG, Basel