STIMULANTS OF ILEAL SALT TRANSPORT IN NEUROENDOCRINE SYSTEM OF THE DESERT LOCUST
STIMULANTS OF ILEAL SALT TRANSPORT IN NEUROENDOCRINE SYSTEM OF THE DESERT LOCUST
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DOI:
10.1016/0016-6480(90)90156-g
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发表时间:
1990-10-01
影响因子:
2.7
通讯作者:
PHILLIPS, JE
中科院分区:
文献类型:
--
作者:
AUDSLEY, N;PHILLIPS, JE
Proteinacenous factors from the corpora cardiaca (CC) and ventral ganglia (VG) stimulate KCl transport across voltage-clamped preparations of locust ilea in a dose-dependent manner. These factors may act via cAMP as the second messenger because this cyclic nucleotide and agents which increase its cellular level all mimic the stimulatory effects of CC and VG extracts. The CC and VG factors are apparently different compounds because they differ in the time course of ileal short-circuit current (Isc) initiated, in heat stability, and in extraction properties. Because saline extracts of the CC have similar effects on both ileal and rectal segments of locust hindgut, the ileal stimulant from the CC may be the chloride transport-stimulating hormone, described by Philips et al. (Canad. J. Zool. 58, 1851-1860, 1980) which acts to stimulate rectal Isc.