Stress and the brain
Stress and the brain
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DOI：
10.1016/s0197-4580(03)00048-4
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发表时间：
2003-05-01
影响因子：
4.2
通讯作者：
Lammers, CH
中科院分区：
文献类型：
--
作者：
Heuser, I;Lammers, CH
压力是多种疾病的危险因素，涉及相同的激素，确保在压力时期的生存。虽然压力的定义相当模糊，但一个有用的操作定义是：“任何诱导糖皮质激素分泌增加的东西”。大脑是糖皮质激素的主要靶点。然而，糖皮质激素诱导的脑损伤的确切机制尚不清楚，旨在调节糖皮质激素异常水平的治疗策略值得研究。(C)2003年爱思唯尔科学公司All rights reserved.
Stress is a risk factor for a variety of illnesses, involving the same hormones that ensure survival during a period of stress. Although there is a considerable ambiguity in the definition of stress, a useful operational definition is: "anything that induces increased secretion of glucocorticoids".The brain is a major target for glucocorticoids. Whereas the precise mechanism of glucocorticoid-induced brain damage is not yet understood, treatment strategies aimed at regulating abnormal levels of glucocorticoids, are worth examining. (C) 2003 Elsevier Science Inc. All rights reserved.