Outcome of patients undergoing prolonged mechanical ventilation after critical illness
Outcome of patients undergoing prolonged mechanical ventilation after critical illness
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DOI：
10.1097/01.ccm.0000287589.16724.b2
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发表时间：
2007-11-01
影响因子：
8.8
通讯作者：
Gettings, Elise M.
中科院分区：
文献类型：
--
作者：
Bigatello, Luca M.;Stelfox, Henry Thomas;Gettings, Elise M.
目的：研究一组危重病后进入急性呼吸监护病房的机械通气患者的纵向结局。设计、设置和患者。前瞻性、观察性研究，纳入了210例急性危重病伴呼吸衰竭、入住急性三级护理大学医院呼吸科的连续患者。本研究的动力是建立多变量回归模型，以研究患者特征与a）脱离机械通气和B）存活率之间的关系。干预：无。测量和主要结果：呼吸单元入院后脱离机械通气的中位时间为14天（四分位数范围，6-51）。共有146例患者（69%）在6个月时脱离机械通气，123例患者（61%）在1年时存活。在呼吸科未脱离机械通气的患者在一年内死亡的可能性是脱离机械通气的患者的7倍（比值比，6.55; 95%可信区间，4.04-10.63; p
Objective: To examine the longitudinal outcome of a cohort of mechanically ventilated patients admitted to an acute care respiratory unit after critical illness.Design, Setting, and Patients., Prospective, observational study of 210 consecutive patients admitted to a respiratory unit of an acute, tertiary care university hospital, who had an acute critical illness with respiratory failure. The study was powered to develop multivariate regression models to investigate the relationship between patient characteristics and a) liberation from mechanical ventilation and b) survival.Interventions: None.Measurements and Main Results: The median time to liberation from mechanical ventilation after respiratory unit admission was 14 days (interquartile range, 6-51). A total of 146 patients (69%) were off mechanical ventilation at 6 months, and 123 patients (61%) were alive at 1 yr. Patients who did not come off mechanical ventilation in the respiratory unit were seven times more likely to die within a year than those who did (odds ratio, 6.55; 95% confidence intervals, 4.04-10.63; p