EFFECT OF BODY ORIENTATION ON REGIONAL LUNG EXPANSION IN DOG AND SLOTH
EFFECT OF BODY ORIENTATION ON REGIONAL LUNG EXPANSION IN DOG AND SLOTH
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DOI：
10.1152/jappl.1985.59.2.481
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发表时间：
1985-01-01
影响因子：
3.3
通讯作者：
RITMAN, EL
中科院分区：
文献类型：
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作者：
HOFFMAN, EA;RITMAN, EL
使用快速多切片X射线计算机断层摄影术，在仰卧狗中显示了部分肺空气含量的腹-背梯度（3.29%空气/cm肺高度），在俯卧狗中显示了基本均匀的腹-背空气含量分布[平均值= 66 ± 0.05]。0.6%（SE）或含量]。由于俯卧方向是犬的正常身体姿势，因此寻找正常身体姿势与犬相反的动物。四只2趾树懒在动态空间重建器中以俯卧和仰卧姿势进行扫描。仰卧位的空气含量梯度分数用回归方程y = 2.09x +74.3（r = 0.92）表示，其中y是空气含量百分比，x是肺中的垂直高度，俯卧位的腹-背空气含量分布均匀，平均值为85 ± 0.01。0.4%（SE）空气含量。树懒的低功能残气量肺密度是由于异常大的肺泡。犬的平均心脏体积与体重比为16.4 ±。0.6（SE）ml/kg，树懒为7.3 ± 0.05。0.4（SE）ml/kg。狗和树懒的平均肺体积与体重的比值为57 ± 0.05。7（SE）和89.+-。6 ml/kg。在犬中发现的俯卧与仰卧胸廓和横膈膜几何结构的较大变化在树懒中未发生，尽管证明了俯卧与仰卧的腹侧和背侧肺几何结构的显著变化，并且犬和树懒中的肺形状变化可归因于纵隔结构胸内位置的变化。
Using fast multisliced X-ray computed tomography, a ventral-dorsal gradient of fractional lung air content (3.29% air/cm lung height) in supine dogs and an essentially uniform ventral-dorsal air content distribution in the prone dogs [mean = 66 .+-. 0.6% (SE) or content] were demonstrated. Since the prone orientation is the dog''s normal body posture, an animal whose normal body posture was opposite to that of the dog was sought. Four 2-toed sloths were scanned in the Dynamic Spatial Reconstructor in the prone and supine postures. A supine fractional air content gradient was demonstrated with a regression equation of y = 2.09x + 74.3 (r = 0.92), where y is percent air content and x is vertical height in the lung, and ventral-dorsal air content distribution in the prone posture was uniform with a mean of 85 .+-. 0.4% (SE) air content. The low functional residual capacity lung density in the sloth was attributable to unusually large alveoli. The mean heart volume-to-body weight ratio in the dogs was 16.4 .+-. 0.6 (SE) ml/kg and that in the sloth was 7.3 .+-. 0.4 (SE) ml/kg. Mean lung volume-to-body weight ratios for dogs and sloths were 57 .+-. 7 (SE) and 89 .+-. 6 ml/kg, respectively. Large changes in prone vs. supine rib cage and diaphragm geometry found in dogs did not occur in sloths, though significant alterations of ventral and dorsal lung geometry prone vs. supine were demonstrated, and lung shape changes in both dog and sloth are attributable to shifts in the intrathoracic position of mediastinal structures.