Quality of life and psychiatric morbidity in panic disorder and generalized anxiety disorder.
Quality of life and psychiatric morbidity in panic disorder and generalized anxiety disorder.
复制标题
恐慌症和广泛性焦虑症的生活质量和精神发病率。
DOI：
10.1176/ajp.150.4.600
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Keller,MB
中科院分区：
文献类型：
--
作者：
Massion,AO;Warshaw,MG;Keller,MB
目的本报告探讨了惊恐障碍和/或广泛性焦虑障碍对生活质量的影响以及这些发现对疾病分类的影响。方法作为针对焦虑症临床人群的前瞻性、自然、纵向、多中心研究的一部分，根据 DSM-III-R 标准，使用结构化临床访谈对总共 357 名当前患有惊恐障碍和/或广泛性焦虑障碍的受试者进行诊断。结果焦虑障碍和重度抑郁障碍高度共存。患有广泛性焦虑症的受试者几乎普遍患有其他疾病，在摄入时最有可能患有至少一种其他焦虑症或重度抑郁症，发病年龄最早，并且情绪健康评级最差。患有恐慌症但没有广场恐惧症的受试者最有可能有酗酒史。百分之九的受试者有自杀企图或自杀行为的历史。结论受试者的生活质量明显受损。其他焦虑症与广泛性焦虑症频繁共存，并且许多生活质量指标总体上缺乏差异，引发了疾病分类学问题，特别是对于广泛性焦虑症。
ObjectiveThis report examines the impact of panic disorder and/or generalized anxiety disorder on quality of life and the implications of these findings on nosological categories.MethodA total of 357 subjects with a current episode of panic disorder and/or generalized anxiety disorder were diagnosed according to DSM-III-R criteria, using structured clinical interviews, as part of a prospective, naturalistic, longitudinal, multicenter study of a clinical population with anxiety disorders.ResultsThere was a high degree of coexistence of anxiety disorders and major depressive disorder. Subjects with generalized anxiety disorder almost universally had other disorders, were the most likely to have at least one other anxiety disorder or major depressive disorder at intake, had the earliest age at onset, and had the worst emotional health rating. Subjects with panic disorder without agoraphobia had the most likelihood of a history of alcohol abuse. Nine percent of the subjects had a history of suicide attempts or gestures.ConclusionsThe subjects showed significant impairment in quality of life. The highly frequent coexistence of other anxiety disorders with generalized anxiety disorder and the overall lack of differences on many quality of life measures raise questions of nosology, particularly for generalized anxiety disorder.