HISTONE CROSS-COMPLEXING PATTERN
HISTONE CROSS-COMPLEXING PATTERN
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DOI：
10.1021/bi00721a019
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发表时间：
1974-01-01
期刊：
影响因子：
2.9
通讯作者：
ISENBERG, I
中科院分区：
文献类型：
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作者：
DANNA, JA;ISENBERG, I
威克特，r.r和伊森伯格，I.(1972)，《科学学报》。69,2687。每个四聚体的Al残基形成螺旋构象。络合抑制ARE和GRK的缓慢聚集。组蛋白ARE和LAK也以1:1的摩尔比相互作用，但在络合时没有增加螺旋度，并且发生缓慢的聚集和/3-sheet形成。ARE和KAS也相互作用，但是，在络合后，酪氨酸刚性或圆二色性没有变化。提出了LAK、KAS、ARE和GRK之间相互作用的模式。更弱（D 'Anna and Isenberg, 1974a）。这些配合物需要盐来保持稳定性，事实上，它们是通过在水中加入盐和组蛋白混合物而形成的。强复合物KAS-中的一个或两个伙伴组蛋白
Wickett, RR, and Isenberg, I.(1972), Proc. Nat. Acad. Sci. US 69, 2687. al residues per tetramer go into an-helical conformation. Complexing inhibits the slow aggregation of ARE and GRK. Histones ARE and LAK also interact in a 1: 1 molar ratio, but there is no increased a helicity upon complexing, and slow aggregation and/3-sheet formation occur. ARE and KAS also interact, but, upon complexing, there is no change in the tyrosine rigidity or in the circular dichroism. A pattern of the interactions between LAK, KAS, ARE, and GRK is presented. more weakly (D’Anna and Isenberg, 1974a). The com-plexes require salt for stability and, in fact, they were formed by adding saltto histone mixtures in water. One or both of the partner histones in the strong complexes, KAS-