Changes in the prevalence of non-medical prescription drug use and drug use disorders in the United States: 1991-1992 and 2001-2002
Changes in the prevalence of non-medical prescription drug use and drug use disorders in the United States: 1991-1992 and 2001-2002
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DOI：
10.1016/j.drugalcdep.2007.04.005
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发表时间：
2007-10-08
影响因子：
4.2
通讯作者：
Hasin, Deborah S.
中科院分区：
文献类型：
--
作者：
Blanco, Carlos;Alderson, Donald;Hasin, Deborah S.
目的：研究1991-1992年和2001- 2002年美国非医疗处方药使用和DSM-IV非医疗处方药滥用和依赖流行率的变化。方法：总样本中和终生非医疗处方药使用者中上年非医疗处方药使用和药物使用障碍流行率的比较两次相隔10年进行的大型全国性调查中的医疗用户。结果：从1991-1992年到2001-2002年，DSM-IV非医疗处方药使用的流行率增加了53%，从1.5%增加到2.3%（p < 0.001），药物使用障碍的患病率从0.3%上升到0.5%，上升了67%（p < 0.001）。用户之间的障碍的条件患病率从19.9%增加到23.6%的数字，但这一增长是没有统计学意义（p = 0.15）。结论：处方药非医疗使用和处方药使用障碍的患病率在美国有大幅增加。鉴于处方药的临床效用，需要采取紧急行动，找到办法，在需要者获得这些药物的需要与脆弱人群滥用和依赖这些药物的可能性之间取得平衡。(C)2007年由Elsevier爱尔兰有限公司出版。
Objective: To examine changes in the prevalence of non-medical prescription drug use and DSM-IV non-medical prescription abuse and dependence in the United States between 1991-1992 and 2001-2002.Method: Comparison of the prevalence of past-year non-medical prescription drug use and drug use disorders in the total sample and among lifetime non-medical users in two large national surveys conducted 10 years apart.Results: From 1991-1992 to 2001-2002, the prevalence of DSM-IV non-medical prescription drug use increased by 53%, from 1.5% to 2.3% (p < 0.001), and the prevalence of drug use disorders increased by 67% from 0.3% to 0.5% (p < 0.001). The conditional prevalence of a disorder among users increased numerically from 19.9% to 23.6%, but this increase was not statistically significant (p = 0.15).Conclusions: There have been substantial increases in the prevalence of prescription drug non-medical use and prescription drug use disorders in the United States. Given the clinical utility of prescription drugs, urgent action is needed to find approaches that balance the need for access to these medications among those who need them, against their potential for abuse and dependence in subgroups of vulnerable individuals. (C) 2007 Published by Elsevier Ireland Ltd.