HapSim: a simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients
HapSim: a simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients
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DOI：
10.1093/bioinformatics/bti689
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发表时间：
2005-12-01
期刊：
影响因子：
5.8
通讯作者：
Montana, G
中科院分区：
文献类型：
--
作者：
Montana, G
我们已经开发了一个模拟工具HapSim的单倍型数据的生成。模拟的单倍型是这样的，它们的等位基因频率和连锁不平衡系数完全匹配那些估计在真实的样本。
We have developed a simulation tool HapSim for the generation of haplotype data. The simulated haplotypes are such that their allele frequencies and linkage disequilibrium coefficients match exactly those estimated in a real sample.