STRATEGY OF DNA SEQUENCING EMPLOYING COMPUTER-PROGRAMS

STRATEGY OF DNA SEQUENCING EMPLOYING COMPUTER-PROGRAMS
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DOI:
10.1093/nar/6.7.2601
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发表时间:
1979-01-01
影响因子:
14.9
通讯作者:
STADEN, R
STADEN, R
中科院分区:
生物学2区
文献类型:
--
作者:
STADEN, R

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随着现代快速测序技术1,2和适当的计算机程序,现在有可能测序整个基因组,而不需要限制性酶切图谱。本文介绍了计算机程序,可以用来订购这两个序列凝胶读数和克隆。描述了凝胶读数不确定度的编码方法。这些程序可应要求提供。
With modern fast sequencing techniques1,2and suitable computer programs it is now possible to sequence whole genomes without the need of restriction maps. This paper describes computer programs that can be used to order both sequence gel readings and clones. A method of coding for uncertainties in gel readings is described. These programs are available on request.