Rhodococcus equi infection in patients with and without human immunodeficiency virus infection.
Rhodococcus equi infection in patients with and without human immunodeficiency virus infection.
复制标题
有或没有人类免疫缺陷病毒感染的患者中的马红球菌感染。
DOI：
10.1093/clinids/13.1.139
复制
发表时间：
1991
期刊：
影响因子：
--
通讯作者：
J. Sunstrum
中科院分区：
文献类型：
--
作者：
R. Harvey;J. Sunstrum
马红球菌是一种罕见的病原体在人类中，偶尔有报告说，造成感染的个人与受损的细胞免疫。我们总结了30个以前发表的报告，人类感染的R。equi和描述一个额外的情况下，艾滋病患者。本报告中讨论的11例患者（35%）患有艾滋病或人类免疫缺陷病毒（HIV）感染，这是R.马传染病77%的患者因R.马，和渗透经常空化。当艾滋病毒感染者与未感染病毒的患者进行比较时，症状，年龄和肺炎的频率相似。在HIV感染者中，痰和血培养更可能呈阳性。与非HIV感染者相比，HIV感染者同时继发感染的发生率和死亡率也更高（54.5%对20%）。当抗生素联合手术切除感染组织时，所有患者的生存率为75%;相比之下，仅接受抗生素治疗的患者的生存率为61.1%。
Rhodococcus equi is an uncommon pathogen in humans that has occasionally been reported to cause infection in individuals with impaired cellular immunity. We summarize 30 previously published reports of human infection with R. equi and describe one additional case in a patient with AIDS. Eleven (35%) of the patients discussed in this report had AIDS or human immunodeficiency virus (HIV) infection, which is emerging as the leading cause of immunosuppression in cases of R. equi infection. Seventy-seven percent of all patients had pneumonia due to R. equi, and the infiltrate frequently cavitated. When HIV-infected patients were compared with those not infected with the virus, symptoms, age, and frequency of pneumonia were similar. Sputum and blood cultures were more likely to be positive in HIV-infected patients. Individuals with HIV infection also had a higher incidence of simultaneous secondary infections and higher mortality than non-HIV-infected patients (54.5% vs. 20%). The rate of survival for all patients was 75% when antibiotics were combined with surgical resection of infected tissue; in comparison, the survival rate among patients receiving antibiotics alone was 61.1%.