COMPREHENSIVE GERIATRIC ASSESSMENT - A METAANALYSIS OF CONTROLLED TRIALS
COMPREHENSIVE GERIATRIC ASSESSMENT - A METAANALYSIS OF CONTROLLED TRIALS
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DOI：
10.1016/0140-6736(93)92884-v
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发表时间：
1993-10-23
期刊：
影响因子：
168.9
通讯作者：
RUBENSTEIN, LZ
中科院分区：
文献类型：
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作者：
STUCK, AE;SIU, AL;RUBENSTEIN, LZ
由于个体试验的结果相互矛盾，对综合老年评估（CGA）的有用性存在分歧。我们对28项对照试验进行了荟萃分析，其中包括4959名被分配到5种CGA类型之一的受试者和4912名对照者。我们用多变量逻辑回归分析从单个试验中收集数据，计算重要结局的合并优势比。老年评估和管理单位、医院-家庭评估服务和家庭评估服务随访时在家生活的合并优势比（95%置信区间）分别为1.68（1.17-2.41）、1.49（1.12-1.98）和1.22（1.05-1.37）。协变量分析显示，控制医疗建议和延长门诊随访的方案更有可能是有效的。我们的分析表明，CGA计划将老年评估与强有力的长期管理联系起来，可有效改善老年人的生存和功能。
There is disagreement on the usefulness of comprehensive geriatric assessment (CGA) due to conflicting results from individual trials. We did a meta-analysis on 28 controlled trials comprising 4959 subjects allocated to one of five CGA types and 4912 controls.Published data were supplemented with reanalysed data provided by the original investigators. We calculated combined odds ratios of important outcomes by pooling data from individual trials with multivariate logistic regression. Combined odds ratio (95% confidence interval) of living at home at follow-up was 1.68 (1.17-2.41) for geriatric evaluation and management units, 1.49 (1.12-1.98) for hospital-home assessment services, and 1.22 (1.05-1.37) for home assessment services. Covariate analysis showed that programmes with control over medical recommendations and extended ambulatory follow-up were more likely to be effective. Our analysis suggests that CGA programmes linking geriatric evaluation with strong long-term management are effective for improving survival and function in older persons.