Olfactory function in children assessed with psychophysical and electrophysiological techniques
Olfactory function in children assessed with psychophysical and electrophysiological techniques
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DOI：
10.1016/j.bbr.2007.02.040
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发表时间：
2007-06-18
影响因子：
2.7
通讯作者：
Schaal, Benoist
中科院分区：
文献类型：
--
作者：
Hummel, Thomas;Bensafi, Moustafa;Schaal, Benoist
儿童的嗅觉信息处理能力在生命早期经历了变化。本研究的目的是描述这些变化，并探讨其电生理相关。这些目标在两个实验中进行了研究。在实验1中，146名受试者（3-12岁）的反应与心理物理工具进行了测试。大约2/3的受试者完成了嗅觉测试（“嗅棒”）。在实验2中，另外12名受试者（3-10岁）进行了测试与电生理工具。用1- 12 S记录嗅觉刺激的事件相关电位（ERP）。从实验一的结果表明，从组的3-5奥尔兹的孩子是非常不可靠的，44%的不完整的措施，使测试不适合常规使用与3-5岁的奥尔兹。结果表明，从6岁开始，嗅觉功能的发展已经很好地推进，仅在气味识别方面有显著增加，但在气味阈值或气味辨别方面没有显著增加。实验2的结果表明，P2潜伏期随年龄的增长，虽然小样本量必须考虑在这些数据的解释。虽然还需要更多的研究，但这些结果可能会被解释为，随着年龄的增长，儿童对气味刺激的意义会增加。(c)2007 Elsevier B. V.保留所有权利。
The olfactory information processing abilities of children undergo changes during early life. The aims of the present study were to describe these changes and to probe for their electrophysiological correlates. These aims were investigated in two experiments. In Experiment 1, responses of 146 subjects (3-12 years) were tested with psychophysical tools. Approximately 2/3 of the subjects completed the olfactory tests ("Sniffin' Sticks"). In Experiment 2, 12 additional subjects (3-10 years) were tested with electrophysiological tools. Event-related potentials (ERPs) were recorded in response to olfactory stimulation with 1-12S. Results from Experiment I indicated that data from the group of 3-5-year olds were very unreliable, with 44% of incomplete measures rendering the tests unsuitable for routine use with 3-5-year olds. From an age of 6 years on the results suggested that the development of olfactory function was well advanced with a significant increase found only for odor identification, but not for odor thresholds, or odor discrimination. Results from Experiment 2 indicated an increase of the P2 latency with age, although the small sample size has to be considered in the interpretation of these data. While more research is needed, these results may be interpreted such that children attach more meaning to odorous stimuli with age. (c) 2007 Elsevier B.V. All rights reserved.