PREPARATION OF LATEX-PARTICLES WITH COVALENTLY BOUND POLYAMINES, IGG AND MEASLES AGGLUTININS AND THEIR USE IN VISUAL AGGLUTINATION TESTS
PREPARATION OF LATEX-PARTICLES WITH COVALENTLY BOUND POLYAMINES, IGG AND MEASLES AGGLUTININS AND THEIR USE IN VISUAL AGGLUTINATION TESTS
复制标题
DOI：
10.1016/0022-1759(78)90069-8
复制
发表时间：
1978-01-01
影响因子：
2.2
通讯作者：
HUPPERT, J
中科院分区：
文献类型：
--
作者：
QUASH, G;ROCH, AM;HUPPERT, J
羧基化胶乳颗粒被以伯胺和肼基团终止的侧臂取代。将颗粒偶联到用高碘酸钠处理的糖蛋白上产生的醛基。具有脂溶性伯胺腐胺半抗原作为唯一取代基的颗粒和与糖蛋白如麻疹凝集素和IG [免疫球蛋白] G连接的颗粒用于通过凝集试验检测生物流体中相应抗体或抗原的存在。
Carboxylated latex particles were substituted with side arms terminating in primary amine and hydrazine groups. The particles were coupled to aldehyde groups generated on glycoproteins which were treated with sodium periodate. Particles having the alipathic primary amine putrescine hapten as the sole substituent and particles linked to glycoproteins such as measles agglutinins and Ig[immunoglobulin]G were used to detect the presence of the corresponding antibodies or antigens in biological fluids by agglutination tests.