Hock-a-loogie saliva as a diagnostic specimen for SARS-CoV-2 by a PCR-based assay: A diagnostic validity study.
Hock-a-loogie saliva as a diagnostic specimen for SARS-CoV-2 by a PCR-based assay: A diagnostic validity study.
复制标题
通过基于 PCR 的检测将 Hock-a-loogie 唾液作为 SARS-CoV-2 的诊断样本:诊断有效性研究。
DOI:
10.1016/j.cca.2020.10.004
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发表时间:
2020-12
期刊:
影响因子:
--
通讯作者:
Chen Y
中科院分区:
文献类型:
--
作者:
Fan J;Yu F;Wang X;Zou Q;Lou B;Xie G;Yang X;Chen W;Wang Q;Zhang D;Wang R;Feng B;Dong Y;Huang L;Teng Y;Deng Z;Yu L;Xu K;Sheng J;Zheng S;Chen Y
To clarify the effect of different respiratory sample types on SARS-CoV-2 detection, we collected throat swabs, nasal swabs and hock-a-loogie saliva or sputum, and compared their detection rates and viral loads. The detection rates of sputum (95.65%, 22/23) and hock-a-loogie saliva (88.09%, 37/42) were significantly higher than those in throat swabs (41.54%, 27/65) and nasal swabs (72.31%, 47/65) (P < 0.001). The Ct Values of sputum, hock-a-loogie saliva and nasal swabs were significantly higher than that in throat swabs, whereas no significant difference was observed between sputum and saliva samples. Hock-a-loogie saliva are reliable sample types that can be used to detect SARS-CoV-2, and worthy of clinical promotion.
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