MASIC: A software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features
MASIC: A software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features
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DOI：
10.1016/j.compbiolchem.2008.02.006
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发表时间：
2008-06-01
影响因子：
3.1
通讯作者：
Smith, Richard D.
中科院分区：
文献类型：
--
作者：
Monroe, Matthew E.;Shaw, Jason L.;Smith, Richard D.
液相色谱-质谱（LC）和串联质谱（MS/MS）数据的定量分析是许多蛋白质组学研究必不可少的。我们开发了MASIC(2)，用于在LC-MS/MS分析中准确测量肽丰度和LC洗脱时间。该软件程序使用高效的处理算法，从数据集快速生成质量特定的选定离子色谱图，并提供交互式浏览器，允许用户使用各种选项检查单个色谱图。(C) 2008 Elsevier Ltd版权所有。
Quantitative analysis of liquid chromatography (LC)-mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC(2) to accurately measure peptide abundances and LC elution times in LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms with a variety of options. (C) 2008 Elsevier Ltd. All rights reserved.