The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition
The electronic-cigarette: Effects on desire to smoke, withdrawal symptoms and cognition
复制标题
DOI：
10.1016/j.addbeh.2012.03.004
复制
发表时间：
2012-08-01
影响因子：
4.4
通讯作者：
Soar, Kirstie
中科院分区：
文献类型：
--
作者：
Dawkins, Lynne;Turner, John;Soar, Kirstie
电子烟（电子烟）是通过吸入蒸汽输送尼古丁的电池供电装置。很少有研究评估对渴望和情绪的急性影响，也没有研究探讨对认知的影响。本研究旨在探讨白色超级电子烟对吸烟欲望、尼古丁戒断症状、注意力和工作记忆的影响。86名吸烟者被随机分配到：18 mg尼古丁电子烟（尼古丁），0 mg电子烟（安慰剂）或只是持有电子烟（只是持有）条件。参与者在基线（T1）以及自由使用电子烟5分钟后的5分钟（T2）和20分钟（T3）对他们的吸烟欲望和戒断症状进行评分。一部分参与者完成了字母取消和布朗-彼得森工作记忆任务。20分钟后，与仅保持组相比，尼古丁和安慰剂组的吸烟欲望和尼古丁戒断的某些方面显著降低;尼古丁电子烟在男性中上级优于安慰剂，但在女性中并非如此。与安慰剂相比，尼古丁电子烟在较长的干扰间隔内也改善了工作记忆表现。尼古丁对字母取消性能没有影响。总之，白色超级电子烟在使用后20分钟减轻了吸烟欲望和戒断症状，尽管尼古丁含量对男性更重要。这项研究还首次证明尼古丁电子烟可以增强工作记忆性能。值得进一步评估电子烟的认知影响及其作为戒烟工具的功效。(C)2012爱思唯尔有限公司保留所有权利。
Electronic cigarettes (e-cigarettes) are battery operated devices that deliver nicotine via inhaled vapour. Few studies have evaluated acute effects on craving and mood, and none have explored effects on cognition. This study aimed to explore the effects of the White Super e-cigarette on desire to smoke, nicotine withdrawal symptoms, attention and working memory. Eighty-six smokers were randomly allocated to either: 18 mg nicotine e-cigarette (nicotine), 0 mg e-cigarette (placebo), or just hold the e-cigarette (just hold) conditions. Participants rated their desire to smoke and withdrawal symptoms at baseline (T1), and five (T2) and twenty (T3) minutes after using the e-cigarette ad libitum for 5 min. A subset of participants completed the Letter Cancellation and Brown-Peterson Working Memory Tasks. After 20 min, compared with the just hold group, desire to smoke and some aspects of nicotine withdrawal were significantly reduced in the nicotine and placebo group; the nicotine e-cigarette was superior to placebo in males but not in females. The nicotine e-cigarette also improved working memory performance compared with placebo at the longer interference intervals. There was no effect of nicotine on Letter Cancellation performance. To conclude, the White Super e-cigarette alleviated desire to smoke and withdrawal symptoms 20 min after use although the nicotine content was more important for males. This study also demonstrated for the first time that the nicotine e-cigarette can enhance working memory performance. Further evaluation of the cognitive effects of the e-cigarette and its efficacy as a cessation tool is merited. (C) 2012 Elsevier Ltd. All rights reserved.