Microcysts in the Inner Nuclear Layer, a Nonspecific SD-OCT Sign of Cystoid Macular Edema
Microcysts in the Inner Nuclear Layer, a Nonspecific SD-OCT Sign of Cystoid Macular Edema
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DOI：
10.1167/iovs.14-14056
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发表时间：
2014-05-01
影响因子：
4.4
通讯作者：
Sigler, Eric J.
中科院分区：
文献类型：
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作者：
Sigler, Eric J.
最近，许多作者提出了一种特殊形式的“微囊性黄斑水肿”发生在各种病因的视神经炎和视神经萎缩患者中，是由于逆行性突触变性。该发现是孤立的内核层的光谱域光学相干断层扫描在大多数情况下，并存在于旁，周边和中央黄斑分布。这种观点批判性地回顾了证据，并表明内核层囊样改变是任何原因引起的典型黄斑囊样水肿的早期和非特异性指标，并且该发现可能不是一个独特的实体。
Recently, many authors have propagated the notion that a specific form of "microcystic macular edema" occurs in patients with optic neuritis and optic atrophy of various etiology and is due to retrograde synaptic degeneration. The finding is isolated to the inner nuclear layer on spectral-domain optical coherence tomography in most cases, and is present in a parafoveal, circumferential, and central macular distribution. This perspective critically reviews the evidence and suggests that inner nuclear layer cystoid changes are an early and nonspecific indicator of typical cystoid macular edema of any cause, and that the finding is likely not a distinct entity.